Results 21 to 30 of about 57,785 (264)
Damping of Epidemic Waves [PDF]
Proceedings of the National Academy of Sciences, 1945 Not ...
Wilson, Edwin B., Worcester, Jane
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PharmaceuticalsBackground: Hepatocellular carcinoma is one of the leading causes of cancer-related deaths worldwide. Its high recurrence rate and limited treatment options underscore the urgent need for the development of new and highly effective drugs.
Jiageng Guo +8 more
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Frontiers in Oncology, 2022 BackgroundDamp-heat syndrome is one of the most important syndrome types in the traditional Chinese medicine (TCM) syndrome differentiation and treatment system, as well as the core pathogenesis of pancreatic cancer (PC) which remains a challenge to ...
Juying Jiao +10 more
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How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger
Journal of Extracellular Vesicles, 2020 Innate immunity is a first line of defence against danger. Exogenous pathogen- or microbe-associated molecular patterns (PAMPs or MAMPs) trigger innate immune responses through well-understood cellular pathways.
Yu Xiao +4 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
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Quick Oscillations With Damping
Mathematische Nachrichten, 1979 AbstractA class of n‐th order (n > 1) differential equations with deviating arguments is considered and sufficient conditions are established in order that all bounded quickly oscillatory solutions (i.e. oscillatory solutions whose consecutive zeros have distance which approaches zero) tend to zero at ∞.
Philos, C. G., Staikos, V. A.
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The damped wave equation with singular damping
Proceedings of the American Mathematical Society, 2020 We analyze the spectral properties and peculiar behavior of solutions of a damped wave equation on a finite interval with a singular damping of the form α
Siegl, Petr +2 more
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
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CYP51A1 in health and disease: from sterol metabolism to regulated cell death
Cell Death DiscoveryHow do cells precisely coordinate sterol metabolism with survival and death signals in diverse physiological and pathological contexts? This fundamental question has gained increasing attention as accumulating evidence reveals that enzymes traditionally ...
Fangquan Chen +5 more
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