Results 1 to 10 of about 57,377 (117)

Differentiating Damp‐Heat and Cold‐Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short‐Chain Fatty Acid Profiling [PDF]

MicrobiologyOpen
On the basis of gut microbiota and short‐chain fatty acids (SCFAs), this study aims to identify diagnostic biomarkers for damp‐heat diarrhea and cold‐damp diarrhea. Rat models of damp‐heat diarrhea and cold‐damp diarrhea were established. Changes in body
Hao Zhang, Xia Song, Wenwen Mi, Peng Ji, Yanming Wei, Yongli Hua   +5 more
doaj   +2 more sources

Damage-associated molecular patterns in hepatic ischemia–reperfusion injury: spatiotemporal signatures, biomarker potential, and clinical translation [PDF]

Frontiers in Immunology
Hepatic ischemia–reperfusion injury (HIRI) remains a key contributor to early allograft dysfunction (EAD), post-hepatectomy liver failure, biliary complications, and the underutilization of marginal donor grafts.
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
doaj   +2 more sources

Damp and mould—the big picture. How do we tackle the damp and mould crisis in social housing: lessons from the UK

Frontiers in Environmental Health
The tragic death of 2-year-old Awaab Ishak, from extensive and prolonged exposure to damp and mould that had not been dealt with by the social landlord who owned the property, and other high profile news stories, have alerted social landlords to the damp
Eleanor Benton
exaly   +3 more sources

EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer

Scientific Reports, 2023
Ferroptosis is a form of regulated cell death characterized by oxidative injury-induced lipid peroxidation. However, the detailed protein post-translational modification regulatory mechanism of ferroptosis remains largely unknown.
Yuan Wang, Yang Liu, Cong Wang, Rui Kang, Daolin Tang, Jiao Liu   +5 more
doaj   +1 more source

Extracellular self-DNA induces local inhibition of growth, regulates production of reactive oxygen species, and gene expression in rice roots

Biologia Plantarum, 2023
The capacity of extracellular self-DNA (esDNA) to inhibit growth is getting more research attention as this could be explored for several purposes, including the development of specific bioherbicides.
T. O. S. TJIA, K. MEITHA, P. SEPTIANI, R. AWALUDIN, D. SUMARDI   +4 more
doaj   +1 more source

ACSS2-mediated NF-κB activation promotes alkaliptosis in human pancreatic cancer cells

Scientific Reports, 2023
Alkaliptosis is a recently discovered type of pH-dependent cell death used for tumor therapy. However, its underlying molecular mechanisms and regulatory networks are largely unknown.
Dongwen Que, Feimei Kuang, Rui Kang, Daolin Tang, Jiao Liu   +4 more
doaj   +1 more source

HMGB1 is a mediator of cuproptosis-related sterile inflammation

Frontiers in Cell and Developmental Biology, 2022
Cuproptosis is a recently recognized modality of cell death driven by intracellular copper-dependent mitochondrial stress. However, the mediators of the sterile inflammatory response to cuproptotic death are undetermined.
Jiao Liu, Yang Liu, Yuan Wang, Rui Kang, Daolin Tang   +4 more
doaj   +1 more source

An independent predictor of poor prognosis in locally advanced rectal cancer: rs867228 in formyl peptide receptor 1 (FPR1)

OncoImmunology, 2021
Formyl peptide receptor 1 (FPR1) plays a key regulatory role in innate and adaptive immunity. Recently, we reported that the CC genotype of FPR1-E346A (rs867228, c. 1037 A > C) is an independent biomarker for patients with locally advanced rectal cancer (
Shu-Fen Chiang, Kevin Chih-Yang Huang, William Tzu-Liang Chen, Tsung-Wei Chen, Tao-Wei Ke, K. S. Clifford Chao   +5 more
doaj   +1 more source

Risk factors for moisture damage presence and severity in Finnish homes

Buildings & Cities, 2023
Moisture-damaged buildings are a prominent issue in Finland, but with limited information on damage prevalence, degree of severity and risk factors. This paper analyses 14,996 Finnish detached and semidetached houses that have undergone a standardised ...
Jonathon Taylor, Anniina Salmela, Martin Täubel, Antti Heimlander, Anne M. Karvonen, Toni Pakkala, Jukka Lahdensivu, Juha Pekkanen   +7 more
doaj   +1 more source

The dark side of ferroptosis in pancreatic cancer

OncoImmunology, 2021
Drug-induced ferroptosis, an iron-dependent regulatory necrosis, has been proposed for the therapy of pancreatic ductal adenocarcinoma. However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key ...
Jiao Liu, Enyong Dai, Rui Kang, Guido Kroemer, Daolin Tang   +4 more
doaj   +1 more source