Stanozolol and Danazol Have Different Effects on Hematopoiesis in the Murine Model of Immune-Mediated Bone Marrow Failure [PDF]
Frontiers in Medicine, 2021 Background: Stanozolol and danazol are widely used in the treatment of aplastic anemia; however, their mechanisms of action are unclear.Methods: Bone marrow mononuclear cells from 10 patients newly diagnosed with aplastic anemia and 10 healthy volunteers
Hongmin Li +3 more
doaj +2 more sources
Biomedicines, 2020 A link between telomere shortening and oxidative stress was found in aging people and patients with cancer or inflammatory diseases. Extracts of Astragalus spp. are known to stimulate telomerase activity, thereby compensating telomere shortening.
I. Guinobert +12 more
semanticscholar +3 more sources
Reactions Weekly, 2020 A comprehensive profile of danazol describing the nomenclatures, formulae, elemental composition, appearance, uses and applications is presented. The profile contains the method which was utilized for the preparation of the drug substance and its ...
A. Al-Badr
semanticscholar +3 more sources
Women's HealthBackground: Danazol is a synthetic progestin with androgenic effects that is approved by the Food and Drug Administration for treatment of endometriosis, benign fibrocystic breast disease, and hereditary angioedema. In recent years, increasing numbers of
Ava Scatoni +6 more
semanticscholar +2 more sources
Evaluating the Efficacy of Levonorgestrel Intrauterine System and Danazol for Relief of Postoperative Pain in Endometriosis. [PDF]
Journal of Clinical and Diagnostic Research, 2017 INTRODUCTION Endometriosis is an oestrogen-dependent disorder, manifests during reproductive years and is associated with pain and infertility. There is considerable debate about the effectiveness of various interventions for pain relief.
Ashima Taneja +5 more
semanticscholar +2 more sources
Respirology Case Reports, 2020 We report the case of a 42‐year‐old female with a history of finger clubbing which improved during pregnancy, a history of unexplained hepatosplenomegaly, and subsequent non‐specific interstitial pneumonia with respiratory failure.
D. Chambers +5 more
semanticscholar +2 more sources
Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat. [PDF]
Front PharmacolBackgroundDanazol is regularly used as a prophylactic treatment in patients with Hereditary angioedema due to C1-inhibitor deficiency (HAE-C1INH). However, this drug is characterized by a risk of drug-drug interactions (DDIs).
Zanichelli A +25 more
europepmc +2 more sources
Danazol: An Effective Option in Acquired Amegakaryocytic Thrombocytopaenic Purpura [PDF]
Case Reports in Hematology, 2015 Acquired amegakaryocytic thrombocytopaenic purpura (AATP) is a rare haematological condition characterised by isolated thrombocytopaenia with normal other cell lines.
E. Mulroy, S. Gleeson, S. Chiruka
doaj +2 more sources
Danazol improves thrombocytopenia in HCV patients treated with peginterferon and ribavirin
Annals of Hepatology, 2011 Background. Thrombocytopenia is a common hematologic disorder observed in patients with chronic hepatitis C virus (HCV) infection. Combined peginterferon (PEG-INF) and ribavirin treatment may exacerbate thrombocytopenia in patients with HCV.Objective ...
Guillermo Cabrera Álvarez +7 more
doaj +2 more sources
Rapid early remission in a patient with severe aplastic anemia: a case report of hetrombopag, cyclosporine, and danazol combination therapy. [PDF]
Front ImmunolSevere aplastic anemia (SAA) is a life-threatening bone marrow failure syndrome that is caused primarily by immune-mediated destruction of hematopoietic stem cells.
Dai Y, Guo Q, Guo X, Liu Q.
europepmc +2 more sources