Anesthesiology, 2018 What We Already Know about This TopicPrompt availability of dantrolene is important for treating malignant hyperthermia and has resulted in lowered mortality ratesMaintaining a malignant hyperthermia cart and full treatment dose of dantrolene is ...
P. Ho +4 more
semanticscholar +1 more source
Fatal Recrudescence of Malignant Hyperthermia in an Infant with Moebius Syndrome
Brazilian Journal of Anesthesiology, 2013 Background and objectives: Malignant hyperthermia (MH) is a pharmacogenetic skeletal muscle disorder characterized by a hypermetabolic state after anesthesia with succinylcholine and/or volatile anesthetics. Various neuromuscular syndromes are associated
Cláudia Regina Fernandes +4 more
doaj +1 more source
Study on contraction and relaxation of experimentally denervated and immobilized muscles: Comparison with dystrophic muscles [PDF]
The contraction-relaxation mechanism of experimentally denervated and immobilized muscles of the rabbit is examined. Results are compared with those of human dystrophic muscles, in order to elucidate the role and extent of the neurotrophic factor, and ...
Hazama, R. +4 more
core +1 more source
Antipsychotic dose escalation as a trigger for Neuroleptic Malignant Syndrome (NMS): literature review and case series report [PDF]
, 2012 Background: “Neuroleptic malignant syndrome” (NMS) is a potentially fatal idiosyncratic reaction to any medication which affects the central dopaminergic system. Between 0.5% and 1% of patients exposed to antipsychotics develop the condition.
AL Pelonero +34 more
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The Neuroleptic Malignant Syndrome: Do we Know Enough? [PDF]
, 2011 The Neuroleptic Malignant Syndrome (NMS) is a potentially grave adverse reaction to oral or parenteral neuroleptic therapy that may be an underdiagnosed and easily overlooked clinical problem.
Ali, MD, Ali Hassan M.
core +1 more source
Clinical and functional effects of a deletion in a COOH-terminal lumenal loop of the skeletal muscle ryanodine receptor [PDF]
, 2017 We have identified a patient affected by a relatively severe form of central core disease (CCD), carrying a heterozygous deletion (amino acids 4863-4869) in the pore-forming region of the sarcoplasmic reticulum calcium release channel.
Girard, Thierry +9 more
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Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle [PDF]
, 2003 SummaryDNA methylation is a covalent biochemical modification controlling chromatin structure and gene expression. Exercise elicits gene expression changes that trigger structural and metabolic adaptations in skeletal muscle.
Barrès, Romain +9 more
core +1 more source
Malignant hyperthermia and dantrolene sodium
Korean Journal of Anesthesiology, 2018 in Korea. The patient was treated with conventional methods including dantrolene, but the patient’s condition became aggravated, requiring the application of an extracorporeal membrane oxygenator (ECMO) to support cardiopulmonary resuscitation [1 ...
Ha Jung Kim +4 more
semanticscholar +1 more source
Intravenous Dantrolene Does Not Exhibit Calcium Channel Blocking Effects on the Cardiac Conduction System in Humans [PDF]
, 1991 M. Kentsch +3 more
openalex +1 more source
Transient transfection induces different intracellular calcium signaling in CHO K1 versus HEK 293 cells [PDF]
, 2018 For the controlled production of recombinant proteinsin mammalian cells by transient transfection, it maybe desirable not only to manipulate, but also todiagnose the expression success early.
Connor, J., Preuss, A., Vogel, H.
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