Results 101 to 110 of about 6,108 (207)

Dantrolene Induces Mitigation of Myocardial Ischemia-Reperfusion Injury by Ryanodine Receptor Inhibition

, 2022
The impairment of intracellular calcium homeostasis plays an essential role during ischemia-reperfusion injury. Calcium release from sarcoplasmic reticulum which is triggered by myocardial ischemia is mainly mediated by ryanodine receptors.
Samiotis, I., Vasileiadis, I., Kotanidou, A., Papalois, A., Deftereos, S., Dedeilias, P., Papakonstantinou, N.A.   +6 more
core  

Dantrolene Sodium이 쥐간 Lysosome의 막 투과도에 미치는 영향

, 1984
의학과/박사[영문] [한글] 임상에서 muscle spasticity로 유발된 악성고열의 치료에 널리 사용되고 있는 dantrole nesodium의 부작용중 대표적인 것으로 hepatotoxicity를 들수 있다(Ogburn등, 1976: Schn eider 및 Mitchell, 1976; Utili등,1977). 인체에서 보고된 바에 의하면 dantrolene sodi um투여시 나타나는 간장기능의 변차를 보면 1) 혈청내 glutamic
홍창호
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Effect of dantrolene sodium on [3H]nitrendipine binding to rat cardiac plasma membranes

, 1985
Dantrolene sodium (Dantrium) has antiarrhythmic activity in addition to its direct-acting skeletal muscle relaxant activity. Dantrolene sodium exerts its skeletal muscle relaxant action by reducing Ca2+ release for sarcoplasmic reticulum.
S M Demuth, R L White, S F Pong
core   +1 more source

Malignant hyperthermia and the dilemma of Dantrolene’s unavailability: a case report

Journal of the Pakistan Medical Association
Malignant Hyperthermia (MH) is a rare disorder which is triggered in genetically susceptible individuals when exposed to non-depolarising muscle relaxant (Succinylcholine) and inhalational anaesthetics (Isoflurane, Desflurane, Sevoflurance, Halothane ...
Abdullah Mahmood, Muhammad Faizan Abbasi, Lubna Shafiq, Sumiya Khan, Muaaz Mahmood, Saqib Mehmood Khan   +5 more
doaj   +1 more source

Dantrolene protects erythrocytes against oxidative stress during whole-body irradiation in rats

, 2003
In our study, we examined the radioprotective effects of dantrolene against gamma irradiation-induced damage of blood cells after total body irradiation of rats. Rats were divided into three groups of eight rats each.
BÜYÜKOKUROĞLU, MEHMET EMİN, KOÇ, MEHMET, Bakan, Nuri, TAYSI, SEYİTHAN   +3 more
core   +1 more source

Loose-patch clamp analysis applied to voltage-gated ionic currents following pharmacological ryanodine receptor modulation in murine hippocampal cornu ammonis-1 pyramidal neurons

Frontiers in Physiology
IntroductionThe loose-patch clamp technique was first developed and used in native amphibian skeletal muscle (SkM), offering useful features complementing conventional sharp micro-electrode, gap, or conventional patch voltage clamping.
Federico Bertagna, Federico Bertagna, Shiraz Ahmad, Rebecca Lewis, Rebecca Lewis, S. Ravi P. Silva, S. Ravi P. Silva, Johnjoe McFadden, Johnjoe McFadden, Christopher L.-H. Huang, Christopher L.-H. Huang, Christopher L.-H. Huang, Hugh R. Matthews, Kamalan Jeevaratnam, Kamalan Jeevaratnam   +14 more
doaj   +1 more source

Sub-chronic dantrolene treatment rescues LTP on RyR inhibition in 3xTg-AD mice.

, 2013
(A–B) Left, graphs show averaged time course of LTP from NonTg and 3xTg-AD mice that were given daily injections of 0.9% saline (A, n = 7 for NonTg, n = 7 for 3xTg-AD) or 10 mg/kg dantrolene (B, n = 10 for NonTg, n = 14 for 3xTg-AD) for 4 weeks.
Megan B. Miller (292322), Benjamin G. Cameransi (292337), Joyce Kim (292328), Corinne Schneider (292326), Jill C. Richardson (292333), Ivan Goussakov (292324), Jaime Wicks (292331), Shreaya Chakroborty (292318), Vincent Conklin (292335), Clark Briggs (292320), Grace E. Stutzmann (292339)   +10 more
core   +1 more source

Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review

, 2019
Editor's Perspective What We Already Know about This Topic Dantrolene effectively treats malignant hyperthermia, but there are discrepant recommendations for dantrolene availability in facilities that stock succinylcholine for airway rescue but do not ...
Multicenter Perioperative Outcomes Group
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The Anesthesiologists’ Perception of Malignant Hyperthermia and Availability of Dantrolene in China: A Cross-Sectional Survey

Risk Management and Healthcare Policy
Jiechu Wang,1– 3,* Yao Yu,1,* Ya Gao,1– 3,* Tingting Wan,1– 3 Zhukai Cong,1– 3 Zhengqian Li,1– 3 Yang Zhou,1– 3 Xiaoxiao Wang,4 Luyang Feng,1– 3 Yongzheng Han,1– 3 Jing Zhang,1– 3 Yinyin Qu,1– 3 Xiangyang Guo1– 3 1Department of Anesthesiology,
Wang J, Yu Y, Gao Y, Wan T, Cong Z, Li Z, Zhou Y, Wang X, Feng L, Han Y, Zhang J, Qu Y, Guo X   +12 more
doaj  

Probable Malignant Hyperthermia Presenting With Refractory Hypotension in a Young Trauma Patient: A Case Report. [PDF]

A A Pract
Azar MY, Azar JH, Azar AE.
europepmc   +1 more source