Results 91 to 100 of about 1,955 (161)

Dantrolene Sodium: Effects on Crustacean Muscle

, 1974
The effect of dantrolene sodium, a muscle relaxant effective on vertebrate skeletal muscle, has been studied on the stretcher muscle of a crab (Callinectes sapidus).
L. L. Odette, H. L. Atwood
core   +1 more source

Calcium-directed therapy in acute pancreatitis

Медицина неотложных состояний
Background. Acute pancreatitis (AP) is a common and potentially life-threatening disease with high rates of complications and mortality. One of its key pathogenic mechanisms is disruption of calcium homeostasis in pancreatic acinar cells.
С.М. Чуклін, С.С. Чуклін
doaj   +1 more source

In vitro binding of dantrolene to bovine serum albumin and rabbit red blood cell ghosts

, 1982
The binding of dantrolene to rabbit red blood cell (RBC) ghosts and bovine serum albumin as models of receptor sites was studied using fluorescence techniques.
M. Mahmoudian, A. R. Dehpour
core   +1 more source

Dantrolene and suxamethonium [PDF]

Anaesthesia, 1980
openaire   +3 more sources

Dantrolene blocks intracellular calcium release in smooth muscle: competitive antagonism of thromboxane A₂

, 1978
Dantrolene sodium has been shown to block the release of intracellular calcium in skeletal muscle. It has been proposed that dantrolene blocks the movement and (or) action of a natural calcium ionophore.
S. C. Cunnane, M. Karmazyn, R. A. Karmali, D. F. Horrobin, M. S. Manku, R. O. Morgan, A. I. Ally   +6 more
core   +1 more source

The Effectiveness of a Mobile National Remote Emergency System for Malignant Hyperthermia in China: Retrospective Pre-Post Implementation Study

Journal of Medical Internet Research
BackgroundMalignant hyperthermia (MH) seriously threatens perioperative safety. Historically, limited awareness of MH among anesthesiologists and the unavailability of dantrolene have caused a high mortality rate of MH events in China.
Lingcan Tan, Hong Yu, Yunxia Zuo, Bin Liu, Tao Zhu, Xiaoqian Deng   +5 more
doaj   +1 more source

Sub-chronic dantrolene treatment normalizes PPF in 3xTg-AD mice.

, 2013
PPF was measured at an interstimulus interval of 50 ms. (A–B) Bar graphs show paired pulse ratio from: (A) Saline-treated NonTg (n = 5) and 3xTg-AD (n = 8) mice with bath application of 10 µM dantrolene; (B) Sub-chronic dantrolene-treated NonTg (n = 12 ...
Megan B. Miller (292322), Benjamin G. Cameransi (292337), Joyce Kim (292328), Corinne Schneider (292326), Jill C. Richardson (292333), Ivan Goussakov (292324), Jaime Wicks (292331), Shreaya Chakroborty (292318), Vincent Conklin (292335), Clark Briggs (292320), Grace E. Stutzmann (292339)   +10 more
core   +1 more source

Effect of dantrolene on baseline cardiac haemodynamics (mean ± SD).

, 2018
Effect of dantrolene on baseline cardiac haemodynamics (mean ± SD).
Min Ru Qui (5851712), Kumud K. Dhital (5851715), Ling Gao (429702), Mark Hicks (5851706), Aoife Doyle (5851709), Peter S. Macdonald (277595), Andrew Jabbour (5851718), Hong C. Chew (5851703), Jeanette E. Villanueva (5851700)   +8 more
core   +1 more source

Dantrolene paradoxically exacerbates short-term brain glucose hypometabolism, hippocampal damage and neuroinflammation induced by status epilepticus in the rat lithium-pilocarpine model

Status epilepticus (SE) is a neurologic emergency characterized by prolonged or rapidly recurring seizures. Increased intracellular calcium concentration ([Ca2+]i) occurring after SE is a key mediator of excitotoxicity that contributes to the brain ...
Gómez Oliver, Francisca, Fernández de La Rosa, Rubén, García García, Luis, Pozo García, Miguel Ángel   +3 more
core   +1 more source

Dantrolene-Responsive Muscle Stiffness in a Patient With a Normal Neurologic Exam and EMG: A Case Report

Case Reports in Neurological Medicine
Muscle stiffness or rigidity is a common problem yet is addressed in few studies. Patients with muscle rigidity/spasticity due to injury of upper motor neurons or genetic muscle diseases are sometimes treated with dantrolene.
Adam S. Deardorff, Matthew J. Burford, Mark M. Rich   +2 more
doaj   +1 more source