Results 151 to 160 of about 6,108 (207)

Dantrolene in severe tetanus

Intensive Care Medicine, 1988
In its most severe form tetanus is treated with prolonged use of neuromuscular blockade, and artificial ventilation. We report a case in which the use of dantrolene sodium shortened the period of artificial ventilation.
I, Farquhar, A, Hutchinson, J, Curran
core   +4 more sources

In vitroantioxidant properties of dantrolene sodium

Pharmacological Research, 2001
Dantrolene sodium is a skeletal muscle relaxant, which inhibits intracellular Ca2+ release from the sarcoplasmic reticulum. The aim of this study is to examine possible in vitro antioxidant effects of dantrolene sodium.
Mehmet Emin Büyükokuroğlu, Ilhami Gulcin, Munir Oktay   +2 more
exaly   +2 more sources

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Dantrolene

Drugs, 2012
Eugene M Sorkin, Sorkin Eugene M
exaly   +2 more sources

Dantrolene requires Mg 2+ to arrest malignant hyperthermia

Proceedings of the National Academy of Sciences of the United States of America, 2017
Malignant hyperthermia (MH) is a clinical syndrome of skeletal muscle that presents as a hypermetabolic response to volatile anesthetic gases, where susceptible persons may develop lethally high body temperatures.
Xaver Koenig, Bradley S Launikonis, Launikonis Bradley S   +2 more
exaly   +3 more sources

Dantrolene and suxamethonium

Anaesthesia, 1979
A single oral dose of dantrolene (100--150 mg) given at least 2 hr pre-operatively has been found to reduce significantly the strength of muscular fasciculations, the hyperkalaemia and the incidence of muscle pains following suxamethonium (from 56 to 4%) in a series of forty-eight patients compared with controls.
openaire   +2 more sources

Hyperkalemia after Dantrolene and Verapamil-Dantrolene Administration in Dogs

Anesthesia & Analgesia, 1988
The concurrent administration of dantrolene and verapamil has the theoretical advantage of being more efficacious than dantrolene alone in the treatment of malignant hyperthermia. However, the combination has been reported to cause fatal hyperkalemia in pigs.
A C, San Juan, K C, Wong, J D, Port
openaire   +2 more sources