Results 11 to 20 of about 4,970 (234)

Synergistic antiarrhythmic mechanism of I Na-L and RyR2 blockade: normalization of pathological calcium cycling and CaMKII signaling [PDF]

Journal of Translational Medicine
Background Arrhythmias represent a leading cause of mortality among individuals with cardiovascular diseases. Considering the failure of antiarrhythmic drugs targeting single-ion channels in clinical trials, this study aims to evaluate the ...
Miaomiao Ju, Suhua Qiu, Yi Wang, Wenting Wu, Jinglei Sun, Chenxia Shi, Qingzhong Jia, Yanfang Xu   +7 more
doaj   +2 more sources

Clinical Research for Inherited Retinal Disease Related Pediatric Blindness: A Preliminary Descriptive Analysis Based on ClinicalTrials.gov [PDF]

Journal of Multidisciplinary Healthcare
Ahmed M Ashour,1,2 Maan H Harbi,1 Fahad S Alshehri,1,2 Saad M Wali,1 Mohammed M Aldurdunji,3 Nasser M Alorfi1 1Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia; 2King Salman Center for ...
Ashour AM, Harbi MH, Alshehri FS, Wali SM, Aldurdunji MM, Alorfi NM   +5 more
doaj   +2 more sources

Dantrolene Sodium [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources

Novel Treatment Using Intravenous Dantrolene Sodium for Postoperative Exacerbated Spasticity in Multiple Sclerosis: A Case Report. [PDF]

A A Pract, 2018
Sturgill EL, Wittwer RL.
europepmc   +3 more sources

Transforming a traditional ethnic beverage into highly emissive CDs as a sensitive nanosensor for the anti-malignant hyperthermia drug dantrolene sodium in pharmaceuticals and plasma. An economic and sustainable approach

Talanta Open
This work provides a cost-effective, environmentally benign, rapidly prepared, highly fluorescent carbon dots (CDs) using renewable antioxidants-rich feedstock (Tamarindus Indica L.) as the precursor.
Samar Salem, Rania El-Shaheny, Nora A. Abdallah   +2 more
doaj   +2 more sources

GERMINE MONOACETATE COUNTERACTS DANTROLENE SODIUM [PDF]

Anesthesiology, 1980
C. Lee, Elizabeth H. Au, N. N. Durant, Ronald L. Katz   +3 more
openalex   +2 more sources

Postoperative Malignant Hyperthermia-A Medical Emergency: A Case Report and Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2017
Malignant hyperthermia is a rare life threatening pharmacological disorder. Preoperative clinical diagnosis is not possible. Due to its rarity and severity, it must be taken as an important differential diagnosis for postoperative hyperthermia.
Amit Kumar Sinha, Poonam Kumari, Maheshkumar Manilal Vaghela, Chandni Sinha, Bindey Kumar   +4 more
doaj   +1 more source

Malignant Hyperthermia Like Manifestations during Management of Refractory Status Epilepticus

Journal of Neuroanaesthesiology and Critical Care, 2023
Management of refractory status epilepticus is challenging for a neurointensivist consequent to systemic complexities associated with various drugs and modalities involved in its treatment.
Deepti Srinivas, Venkatesh Keshavan, Vikram Kamath, Manju Manmadhan   +3 more
doaj   +1 more source

Delayed-onset malignant hyperthermia in the postanesthetic care unit: a case report

Journal of International Medical Research, 2021
Malignant hyperthermia (MH) is a potentially fatal hypermetabolic syndrome that occurs when susceptible individuals are exposed to triggering agents. Variability in the order and time of occurrence of symptoms often makes clinical diagnosis difficult.
Ji Young Min, Sang Hyun Hong, Sung Jun Kim, Mee Young Chung   +3 more
doaj   +1 more source

Hepatotoxicological Evaluation of Dantrolene Sodium [PDF]

Drug and Chemical Toxicology, 1984
The clinical use of dantrolene has been associated with hepatotoxicity, thus the toxicity of dantrolene in Swiss-Webster mice was characterized. Animals were treated orally (po) with single or multiple doses of up to 400 mg/kg of D without any increases in SGPT or alterations in hepato-cellular architecture.
J A, Durham, A J, Gandolfi, J B, Bentley
openaire   +2 more sources