Delayed-Onset Malignant Hyperthermia in Association with Rocuronium Use [PDF]
, 2012 Purpose Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. Summary A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant ...
Beggs, Ashton E. +2 more
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Korean Journal of Anesthesiology, 2012 Malignant hyperthermia (MH) is an uncommon, life-threatening pharmacogenetic disorder of the skeletal muscle. It presents as a hypermetabolic response in susceptible individuals to potent volatile anesthetics with/without depolarizing muscle relaxants ...
Dong-Chan Kim
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Targeting cellular calcium homeostasis to prevent cytokine-mediated beta cell death [PDF]
, 2017 Pro-inflammatory cytokines are important mediators of islet inflammation, leading to beta cell death in type 1 diabetes. Although alterations in both endoplasmic reticulum (ER) and cytosolic free calcium levels are known to play a role in cytokine ...
Abreu, Damien +9 more
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Binding of dantrolene sodium to muscle intracellular membranes [PDF]
FEBS Letters, 1980 Dantrolene sodium (l- { [5-@-nitrophenyl)furfuryl- idene]amino}hydantoin sodium was synthesized in 1967 [I] and later shown to act as a depressant of muscle contractility. It has proven to be effective in the treatment of various forms of spasticity [2] as well as in the prophylaxis and treatment of the potentially lethal malignant hyperthermia muscle ...
Ernesto Carafoli +2 more
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In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers [PDF]
, 2017 Citation: Wakizaka, M., Eshima, H., Tanaka, Y., Shirakawa, H., Poole, D. C., & Kano, Y. (2017). In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers. Physiological Reports, 5(5), 10.
Eshima, H. +5 more
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Electropermeabilization of inner and outer cell membranes with microsecond pulsed electric field. Quantitative study with calcium ions [PDF]
, 2017 Microsecond pulsed electric fields (mu sPEF) permeabilize the plasma membrane (PM) and are widely used in research, medicine and biotechnology. For internal membranes permeabilization, nanosecond pulsed electric fields (nsPEF) are applied but this ...
Andrã©, Franck M. +4 more
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Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma
Journal of Anaesthesiology Clinical Pharmacology, 2016 Soma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic ...
Gunchan Paul +2 more
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Effects of extracellular Ca++, K+, and Na+ on cone and retinal pigment epithelium retinomotor movements in isolated teleost retinas. [PDF]
, 1984 We have examined the effects of changes in extracellular ionic composition on cone and retinal pigment epithelium (RPE) retinomotor movements in cultured isolated teleost retinas.
BURNSIDE, Beth, Dearry, A
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A Case of Fatal Malignant Hyperthermia During Pes Equinovarus Surgery in a Child
Journal of Pediatric Emergency and Intensive Care Medicine, 2018 Malignant hyperthermia (MH) is a genetic syndrome characterized by hyperthermia, tachycardia, acidosis, and muscle rigidity, often triggered by depolarizing muscle relaxants such as volatile anesthetics and/or succinylcholine.
Ümüt Altuğ +5 more
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Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx. [PDF]
, 2016 Retinitis pigmentosa (RP) is a degenerative retinal disease leading to photoreceptor cell loss. In 2011, our group identified the synthetic progesterone ‘Norgestrel’ as a potential treatment for RP.
Byrne, Ashleigh M. +5 more
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