Results 31 to 40 of about 479,392 (208)

Effect of acupoint catgut embedding on intestinal mucosal epithelial barrier in ulcerative colitis rats

open access: yes针刺研究, 2021
Objective To observe the effect of acupoint catgut embedding on intestinal mucosal epithelial injury, and expression of epithelial tight junction proteins and mRNAs and protein kinase C(PKC) protein(intestinal mucosal epithelial barrier-related molecules)
WANG Huan, ZHU Ying, LOU Yu
doaj  

When the governance of algorithms fails: The DAO case

open access: yes, 2023
Este artículo explora los desafíos de la gobernanza algorítmica utilizando el estudio de caso de The DAO, una efímera tentativa de crear una organización autónoma descentralizada en la plataforma de blockchain Ethereum.
Sandoval Archila, Javier
core   +2 more sources

Behavioral Coping With Food Price Inflation: Patterns Among U.S. Households

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Recent food price inflation has placed substantial pressure on household budgets, food security, and mental well‐being. Using Household Pulse Survey data, we combine k‐modes clustering and Double Machine Learning to identify distinct household coping groups and examine differences in how households respond to rising food prices across groups ...
Yuxiang Zhang, Yizao Liu
wiley   +1 more source

Evaluation of the Safety and Tolerability of Three Single Ascending Doses of Diamine Oxidase (DAO) in Healthy Volunteers: A Randomized Clinical Trial

open access: yesInternational Journal of Translational Medicine
Background/Objectives: Diamine oxidase (DAO) enzyme metabolizes dietary histamine in the gastrointestinal tract. DAO deficiency can lead to histamine intolerance (HIT), manifesting as migraines, gastrointestinal disturbances, and allergic reactions.
Pol Molina Perelló   +8 more
doaj   +1 more source

A Memristor‐Based In‐Memory Computing System‐on‐Chip with Efficient Depthwise Convolution

open access: yesAdvanced Intelligent Systems, EarlyView.
We present a memristor‐based in‐memory computing (IMC) architecture that enables efficient depthwise convolution (DWC) acceleration. Fabricated in a system‐on‐chip with crossbar arrays, the design improves memory utilization. Experimental validation demonstrates the first hardware acceleration of DWC in IMC, achieving a digital comparable inference ...
Wenhao Song   +21 more
wiley   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

open access: yesAnnals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl   +10 more
wiley   +1 more source

Molecular basis and functional characterization of human 3-methylcrotonyl-CoA carboxylase deficiency [PDF]

open access: yes, 2009
3-Methylcrotonyl-CoA carboxylase (MCC) deficiency is a rare disorder of leucine catabolism inherited as an autosomal recessive trait. The phenotypic expression of the disease is highly variable, ranging from neonatal onset with severe neurological ...
Dantas, Maria Fernanda
core   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

open access: yesAnimal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian   +8 more
wiley   +1 more source

Diamino oxidase (DAO)-enriched extracts from germinated yellow pea (Pisum sativum L.) for histamine degradation

open access: yesJournal of Agriculture and Food Research
Diamine oxidase (DAO; EC 1.4.3.22) is the main enzyme responsible for breaking down dietary histamine, and its deficiency can lead to histamine intolerance. Management of this condition typically involves a low-histamine diet and oral DAO supplementation.
Aitana Duch-Calabuig   +4 more
doaj   +1 more source

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