Diamine Oxidase Activity Deficit and Idiopathic Rhinitis: A New Subgroup of Non-Allergic Rhinitis? [PDF]
Idiopathic rhinitis represents more than 50% of non-allergic rhinitis, a heterogeneous group that involves the symptomatic inflammation of the nasal mucosa.
Miguel Mayo-Yáñez +5 more
doaj +3 more sources
SYNDROME OF CHILDREN S HISTAMINE INTOLERANCE
Aim. The purpose of the study: to pay attention to the urgency of the problem for further deeper study of diseases in children, which is based on the violation of histamine metabolism in the body, namely, increase in the level of extracellular histamine.
A. V. Burlutskaia, V. N. Firsova
doaj +3 more sources
Background/Objectives: Diamine oxidase (DAO) enzyme metabolizes dietary histamine in the gastrointestinal tract. DAO deficiency can lead to histamine intolerance (HIT), manifesting as migraines, gastrointestinal disturbances, and allergic reactions.
Pol Molina Perelló +8 more
doaj +2 more sources
The Prevalence of Single Nucleotide Polymorphisms of the <i>AOC1</i> Gene Associated with Diamine Oxidase (DAO) Enzyme Deficiency in Healthy Newborns: A Prospective Population-Based Cohort Study. [PDF]
A prospective population-based study was conducted in a sample of 200 healthy newborns aimed to determine the prevalence of diamine oxidase (DAO) enzyme deficiency caused by single nucleotide polymorphisms (SNPs) variants of the AOC1 gene. Genotyping was performed in oral mucosa samples collected around 2 days after birth.
Fortes Marin E +4 more
europepmc +3 more sources
Histamine intolerance is associated with impaired histamine metabolism caused by a deficiency of the enzyme diamine oxidase (DAO). A recommended strategy to alleviate symptoms is a low-histamine diet supplemented with exogenous DAO.
Judit Costa-Catala +5 more
doaj +2 more sources
Association of intestinal mucosal barrier function with intestinal microbiota in Spleen-Kidney Yang Deficiency IBS-D mice [PDF]
BackgroundTo establish and evaluate an IBS-D mouse model with Spleen-Kidney Yang Deficiency, explore the microecological mechanisms of IBS-D, and provide experimental evidence for the clinical diagnosis and treatment of IBS-D with Spleen-Kidney Yang ...
Liwen Li +7 more
doaj +2 more sources
Improvement of Histamine Intolerance Symptoms in Pregnant Women with Diamine Oxidase Deficiency: An Exploratory Study. [PDF]
Background/Objectives: Diamine oxidase (DAO) deficiency can lead to excessive histamine absorption at the intestinal level, triggering symptoms that affect the gastrointestinal, neurological, dermatological, respiratory, circulatory, and musculoskeletal ...
Duelo A +6 more
europepmc +2 more sources
Introduction: The amine oxidase copper-containing 1 (AOC1) gene encodes for the diamine oxidase (DAO) enzyme. DAO is an enzyme that catabolizes some molecules, including histamine, and is the degradative enzyme in the polyamine catabolic pathway that is ...
Gülşah Okutan +11 more
doaj +1 more source
1-methylhistamine as a potential biomarker of food histamine intolerance. A pilot study
Efforts are currently being directed to identify a non-invasive marker that can serve as a solid and clinically irrefutable diagnostic criterion for histamine intolerance associated with diamine oxidase (DAO) deficiency.
Sònia Sánchez-Pérez +17 more
doaj +1 more source
Low serum diamine oxidase (DAO) activity levels in patients with migraine. [PDF]
Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by a deficiency in the enzyme diamine oxidase (DAO).
Duelo, Adriana +6 more
core +1 more source

