Results 1 to 10 of about 517,397 (177)
Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain [PDF]
Biomedicines, 2023 Diamine oxidase (DAO) is an enzyme that metabolizes intestinal histamine. Single nucleotide polymorphisms (SNPs) of the Amine Oxidase Copper Containing 1 (AOC1) gene can lead to low enzymatic activity or functionality in histamine metabolism.
Gülşah Okutan +8 more
doaj +8 more sources
Prevalence of Diamine Oxidase Enzyme (DAO) Deficiency in Subjects With Insomnia-Related Symptoms [PDF]
Journal of Clinical MedicineBackground/Objectives: To assess the prevalence of diamine oxidase (DAO) enzyme deficiency caused by single nucleotide polymorphisms (SNPs) of the AOC1 gene in a sample of patients with symptoms of insomnia. Methods: A total of 167 adult patients (> 18 years of age) with symptoms of insomnia attended in a specialized institute for healthy ...
Júlia Ferrer Garcia
exaly +6 more sources
Histamine intolerance, DAO deficiency and their impact on health in the context of migraine development and treatment: a review [PDF]
Journal of Education, Health and SportIntroduction and purpose Migraine is a prevalent neurological disorder affecting up to 1 billion individuals worldwide. Histamine intolerance, caused by reduced activity of the diamine oxidase enzyme, has been increasingly linked to migraines, with ...
Agata Białek +6 more
doaj +5 more sources
Diamine Oxidase (DAO) Supplement Reduces Headache in Episodic Migraine Patients With DAO Deficiency: A Randomized Double-Blind Trial [PDF]
Clinical Nutrition, 2019 Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by a deficiency in the enzyme diamine oxidase (DAO). Among histamine related symptoms, headache is one of the most recorded. Current clinical strategies for the treatment of the symptomatology related to this disorder
M Carmen Vidal-Carou +2 more
exaly +6 more sources
Histamine intolerance caused by Diamine Oxidase (DAO) deficiency – case report
Journal of Pre-Clinical and Clinical Research, 2022 Histamine is a biogenic amine, which occurs naturally in the human body. Histamine can be metabolised with Diamine Oxidase (DAO) Enzyme. It is estimated that in 1% of people, as a result of an imbalance between the supply and degradation of histamine, a ...
Aleksandra Iwona Zimna +5 more
doaj +6 more sources
International Journal of Translational MedicineBackground/Objectives: Diamine oxidase (DAO) enzyme metabolizes dietary histamine in the gastrointestinal tract. DAO deficiency can lead to histamine intolerance (HIT), manifesting as migraines, gastrointestinal disturbances, and allergic reactions.
Pol Molina Perelló +8 more
doaj +4 more sources
Applied Food ResearchHistamine intolerance is associated with impaired histamine metabolism due to diamine-oxidase (DAO) enzyme deficiency at intestinal level. The recommended strategy to alleviate the symptomatology is a low-histamine diet supplemented with DAO.
Judit Costa-Catala +7 more
doaj +3 more sources
Frontiers in Genetics, 2023 Introduction: The amine oxidase copper-containing 1 (AOC1) gene encodes for the diamine oxidase (DAO) enzyme. DAO is an enzyme that catabolizes some molecules, including histamine, and is the degradative enzyme in the polyamine catabolic pathway that is ...
Gülşah Okutan +11 more
doaj +1 more source
1-methylhistamine as a potential biomarker of food histamine intolerance. A pilot study
Frontiers in Nutrition, 2022 Efforts are currently being directed to identify a non-invasive marker that can serve as a solid and clinically irrefutable diagnostic criterion for histamine intolerance associated with diamine oxidase (DAO) deficiency.
Sònia Sánchez-Pérez +17 more
doaj +1 more source
Diamine Oxidase Activity Deficit and Idiopathic Rhinitis: A New Subgroup of Non-Allergic Rhinitis?
Life, 2023 Idiopathic rhinitis represents more than 50% of non-allergic rhinitis, a heterogeneous group that involves the symptomatic inflammation of the nasal mucosa.
Miguel Mayo-Yáñez +5 more
doaj +1 more source