Results 1 to 10 of about 1,135,021 (120)

Exercising the Sanger Sequencing Strategy for Variants Screening and Full-Length Genome of SARS-CoV-2 Virus during Alpha, Delta, and Omicron Outbreaks in Hiroshima

Viruses, 2022
This study aimed to exercise the Sanger sequencing strategy for screening of variants among confirmed COVID-19 cases and validate our strategy against NGS strains in Hiroshima retrieved from GISAID.
Ko Ko, Kazuaki Takahashi, Shintaro Nagashima, Bunthen E, Serge Ouoba, Toshiro Takafuta, Yoshiki Fujii, Michi Mimori, Fumie Okada, Eisaku Kishita, Kunie Ariyoshi, Md Razeen Ashraf Hussain, Aya Sugiyama, Tomoyuki Akita, Masao Kuwabara, Junko Tanaka   +15 more
doaj   +1 more source

Prevalence of symptoms, comorbidities, and reinfections in individuals infected with Wild-Type SARS-CoV-2, Delta, or Omicron variants: a comparative study in western Mexico

Frontiers in Public Health, 2023
IntroductionThe variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been classified into variants of interest (VOIs) or concern (VOCs) to prioritize global monitoring and research on variants with potential risks to public ...
Marcela Peña Rodríguez, Jorge Hernández Bello, Natali Vega Magaña, Natali Vega Magaña, Oliver Viera Segura, Mariel García Chagollán, Hazael Ramiro Ceja Gálvez, Hazael Ramiro Ceja Gálvez, Jesús Carlos Mora Mora, Francisco Israel Rentería Flores, Francisco Israel Rentería Flores, Octavio Patricio García González, José Francisco Muñoz Valle   +12 more
doaj   +1 more source

Sequencing of SARS-CoV-2 in local transmission cases through Oxford Nanopore MinION platform from Karachi Pakistan

Journal of Infection in Developing Countries, 2021
Introduction: The first case of severe acute respiratory syndrome 2 (SARS-CoV-2) was imported to Pakistan in February 2020, since then 8,260 deaths have been witnessed.
Samina Naz Mukry, Shariq Ahmed, Ali Raza Bukhari, Aneeta Shahni, Gul Sufaida, Arshi Naz, Tahir Sultan Shamsi   +6 more
doaj   +1 more source

FnCas9-based CRISPR diagnostic for rapid and accurate detection of major SARS-CoV-2 variants on a paper strip

eLife, 2021
The COVID-19 pandemic originating in the Wuhan province of China in late 2019 has impacted global health, causing increased mortality among elderly patients and individuals with comorbid conditions.
Manoj Kumar, Sneha Gulati, Asgar H Ansari, Rhythm Phutela, Sundaram Acharya, Mohd Azhar, Jayaram Murthy, Poorti Kathpalia, Akshay Kanakan, Ranjeet Maurya, Janani Srinivasa Vasudevan, Aparna S, Rajesh Pandey, Souvik Maiti, Debojyoti Chakraborty   +14 more
doaj   +1 more source

Detecting Rapid Spread of SARS-CoV-2 Variants, France, January 26–February 16, 2021

Emerging Infectious Diseases, 2021
Variants of severe acute respiratory syndrome coronavirus 2 raise concerns regarding the control of coronavirus disease epidemics. We analyzed 40,000 specific reverse transcription PCR tests performed on positive samples during January 26–February 16 ...
Stéphanie Haim-Boukobza, Bénédicte Roquebert, Sabine Trombert-Paolantoni, Emmanuel Lecorche, Laura Verdurme, Vincent Foulongne, Christian Selinger, Yannis Michalakis, Mircea T. Sofonea, Samuel Alizon   +9 more
doaj   +1 more source

Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer

Cells, 2020
The emergence of immunotherapy has been an astounding breakthrough in cancer treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have shown remarkable therapeutic outcomes.
Andrew M. K. Law, Fatima Valdes-Mora, David Gallego-Ortega   +2 more
doaj   +1 more source

Identification and Characterization of Two Novel Compounds: Heterozygous Variants of Lipoprotein Lipase in Two Pedigrees With Type I Hyperlipoproteinemia

Frontiers in Endocrinology, 2022
BackgroundType I hyperlipoproteinemia, characterized by severe hypertriglyceridemia, is caused mainly by loss-of-function mutation of the lipoprotein lipase (LPL) gene.
Shuping Wang, Shuping Wang, Shuping Wang, Yiping Cheng, Yiping Cheng, Yingzhou Shi, Yingzhou Shi, Wanyi Zhao, Wanyi Zhao, Ling Gao, Ling Gao, Ling Gao, Ling Gao, Li Fang, Li Fang, Xiaolong Jin, Xiaolong Jin, Xiaoyan Han, Xiaoyan Han, Qiuying Sun, Qiuying Sun, Guimei Li, Jiajun Zhao, Jiajun Zhao, Chao Xu, Chao Xu   +25 more
doaj   +1 more source

Molecular and Clinical Epidemiology of SARS-CoV-2 Infection among Vaccinated and Unvaccinated Individuals in a Large Healthcare Organization from New Jersey

Viruses, 2023
New Jersey was among the first states impacted by the COVID-19 pandemic, with one of the highest overall death rates in the nation. Nevertheless, relatively few reports have been published focusing specifically on New Jersey. Here we report on molecular,
José R. Mediavilla, Tara Lozy, Annie Lee, Justine Kim, Veronica W. Kan, Elizabeth Titova, Ashish Amin, Michael C. Zody, André Corvelo, Dayna M. Oschwald, Amy Baldwin, Samantha Fennessey, Jerry M. Zuckerman, Thomas Kirn, Liang Chen, Yanan Zhao, Kar Fai Chow, Tom Maniatis, David S. Perlin, Barry N. Kreiswirth   +19 more
doaj   +1 more source

The Rapid Assessment of Aggregated Wastewater Samples for Genomic Surveillance of SARS-CoV-2 on a City-Wide Scale

Pathogens, 2021
Throughout the course of the ongoing SARS-CoV-2 pandemic there has been a need for approaches that enable rapid monitoring of public health using an unbiased and minimally invasive means.
Eric C. Rouchka, Julia H. Chariker, Kumar Saurabh, Sabine Waigel, Wolfgang Zacharias, Mei Zhang, Daymond Talley, Ian Santisteban, Madeline Puccio, Sarah Moyer, Rochelle H. Holm, Ray A. Yeager, Kevin J. Sokoloski, Joshua Fuqua, Aruni Bhatnagar, Ted Smith   +15 more
doaj   +1 more source

COVID-19 Vaccine Hesitancy among Parents of Children and Adolescents Living in Brazil

Vaccines, 2021
Background: The immunization of large portions of populations in low/middle-income countries is considered one of the key measures to limit the development of new SARS-CoV-2 variants.
Leonardo Evangelista Bagateli, Edna Yayoi Saeki, Marta Fadda, Carlo Agostoni, Paola Marchisio, Gregorio Paolo Milani   +5 more
doaj   +1 more source