Results 91 to 100 of about 2,485 (155)

Decreasing Herpes Simplex Viral Infectivity in Solution by Surface-Immobilized and Suspended N,N-Dodecyl,methyl-polyethylenimine [PDF]

, 2012
Purpose To explore surface-immobilized and suspended modalities of the hydrophobic polycation N,N-dodecyl,methyl-polyethylenimine (DMPEI) for the ability to reduce viral infectivity in aqueous solutions containing herpes simplex viruses (HSVs) 1 and 2.
Klibanov, Alexander M., Knipe, David M., Larson, Alyssa Maxine, Oh, Hyung Suk   +3 more
core   +1 more source

Pre-incubation of cell-free HIV-1 group M isolates with non-nucleoside reverse transcriptase inhibitors blocks subsequent viral replication in co-cultures of dendritic cells and T cells. [PDF]

, 2005
In order to study the inhibitory effect of various reverse transcriptase inhibitors (RTIs) on cell-free HIV, we adapted a recently described in vitro system, based on co-cultures of dendritic cells and resting CD4 T cells, modelling early target cells ...
Andries, Koen, Fransen, K., Garcia, S., Janssen, C.G.M., Janssen, P.A.J., Kestens, Luc, Lewi, Paul, Njai, H.F., Vanham, Guido   +8 more
core  

HIV prevention trial design in an era of effective pre-exposure prophylaxis [PDF]

, 2017
Pre-exposure prophylaxis (PrEP) has demonstrated remarkable effectiveness protecting at-risk individuals from HIV-1 infection. Despite this record of effectiveness, concerns persist about the diminished protective effect observed in women compared with ...
Cuffe, RL, Cutrell, A, Donnell, D, Dunn, DT, Glidden, DV, Grobler, A, Hanscom, B, Meyer, RD, Stancil, BS, Wang, R   +9 more
core   +1 more source

In vitro–ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems

Drug Delivery, 2017
Composite delivery systems where drugs are electrospun in different layers and vary the drug stacking-order are posited to affect bioavailability. We evaluated how the formulation characteristics of both burst- and sustained-release electrospun fibers ...
Anna K. Blakney, Adam B. Little, Yonghou Jiang, Kim A. Woodrow   +3 more
doaj   +1 more source

We choose: Adolescent girls and young women's choice for an HIV prevention product in a cross-over randomized clinical trial conducted in South Africa, Uganda, and Zimbabwe.

PLoS ONE
With new pre-exposure prophylaxis (PrEP) modalities for HIV prevention becoming available, understanding how adolescent girls and young women (AGYW) navigate through PrEP options is essential, including factors underlying their choice.
Millicent Atujuna, Kristin Williams, Sarah T Roberts, Alinda Young, Erica N Browne, Nomvuyo T Mangxilana, Siyanda Tenza, Mary Kate Shapley-Quinn, Thelma Tauya, Kenneth Ngure, Ariane van der Straten   +10 more
doaj   +1 more source

The role of economic evaluations in advancing HIV multipurpose prevention technologies in early-stage development

Frontiers in Reproductive Health
Product development is a high-risk undertaking, especially so when investments are prioritized for low- and middle-income countries (LMICs) where markets may be smaller, fragile, and resource-constrained.
Katerina Chapman, Sergio Torres-Rueda, Mutsumi Metzler, Bethany Young Holt, Elijah Kahn-Woods, Douglas Thornton, Gabriela B. Gomez, Gabriela B. Gomez   +7 more
doaj   +1 more source

Achieving HIV epidemic control through accelerating efforts to expand access to pre-exposure prophylaxis for people who inject drugs

Frontiers in Reproductive Health
The world is not on track to reach the majority of the UNAIDS 2025 targets, and people who inject drugs (PWID) continue to be left behind, hindered by counterproductive law enforcement practices, punitive laws, economic distress, and social stigma and ...
Lirica Nishimoto, Adaobi Lisa Olisa, Philip Imohi, Judy Chang, Chris Obermeyer, Dama Kabwali, Christopher Akolo   +6 more
doaj   +1 more source

Abstract Supplement Abstracts from IAS 2025, the 13th IAS Conference on HIV Science, 13 – 17 July, Kigali, Rwanda & Virtual

Journal of the International AIDS Society, Volume 28, Issue S4, July 2025.
wiley   +1 more source

Contents

Journal of the International AIDS Society, Volume 28, Issue S2, July 2025.
wiley   +1 more source

Microbicide Vaginal Rings: Technological Challenges and Clinical Development [PDF]

, 2016
Boyd, Peter J., Malcolm, R. Karl, McCoy, Clare F., Murphy, Diarmaid J.   +3 more
core   +1 more source