The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC [PDF]
, 2013 BACKGROUND: CSIC (5-chloro-3-phenylsulfonylindole-2-carboxamide), a non-nucleoside reverse transcriptase inhibitor (NNRTI) has not been advanced as a therapeutic anti-HIV candidate drug due to its low aqueous solubility and poor bioavailability ...
Charles O Esimone +4 more
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Treatment And Prevention for female Sex workers in South Africa: protocol for the TAPS Demonstration Project. [PDF]
, 2016 INTRODUCTION: Updated guidelines from the WHO recommend antiretroviral treatment for adults with HIV at any CD4 count and daily oral pre-exposure prophylaxis (PrEP) for people at substantial risk of HIV infection.
Akpomiemie, Godspower +5 more
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Vaginal rings for delivery of HIV microbicides
International Journal of Women's Health, 2012 R Karl Malcolm, Susan M Fetherston, Clare F McCoy, Peter Boyd, Ian MajorSchool of Pharmacy, Queen's University Belfast, Belfast, UKAbstract: Following the successful development of long-acting steroid-releasing vaginal ring devices for the ...
McCoy CF +4 more
doaj
The Medical Research Council (UK)/Uganda Virus Research Institute Uganda Research Unit on AIDS--'25 years of research through partnerships'. [PDF]
, 2014 For the past 25 years, the Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS has conducted research on HIV-1, coinfections and, more recently, on non-communicable diseases.
Elliott, AM +4 more
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The science at HIVR4P 2024: The era of choice in biomedical HIV prevention
Journal of the International AIDS Society, Volume 28, Issue 7, July 2025.ABSTRACT Introduction HIVR4P 2024, the 5th HIV Research for Prevention Conference, took place in Lima, Peru, 6–10 October 2024. The conference focused on new developments in HIV prevention from basic research to new product development and implementation science.
Beatriz Grinsztejn +26 more
wiley +1 more source
2016 Pipeline Report HIV and TB [PDF]
, 2016 HIV and TB: Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in ...
Erica Lessem +7 more
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Coming of age? Women's sexual and reproductive health after twenty-one years of democracy in South Africa [PDF]
, 2016 This paper is a sequel to a 2004 article thet reviewed South Africa's introduction of new sexual and reproductive health (SRH) and rights, laws, policies and programmes, a decade into democracy. Similarly to the previous article this paper focuses on key
Constant, D. +7 more
core +1 more source
Pharmaceutics, 2019 Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention of HIV sexual transmission. We fabricated core-shell poly(lactide-co-glycolide)
Haitao Yang +5 more
doaj +1 more source
Utilization of data below the analytical limit of quantitation in pharmacokinetic analysis and modeling: promoting interdisciplinary debate [PDF]
, 2018 Traditionally, bioanalytical laboratories do not report actual concentrations for samples with results below the LOQ (BLQ) in pharmacokinetic studies.
Atholl Johnston +27 more
core +1 more source
Griffithsin Retains Anti-HIV-1 Potency with Changes in gp120 Glycosylation and Complements Broadly Neutralizing Antibodies PGT121 and PGT126. [PDF]
, 2019 Griffithsin (Grft) is an antiviral lectin that has been shown to potently inhibit HIV-1 by binding high-mannose N-linked glycosylation sites on HIV-1 gp120.
Fischer, Kathryn +2 more
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