Results 61 to 70 of about 2,485 (155)

Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]

, 2019
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A, Deming, Timothy, Elliott, Julie, Fulcher, Jennifer A, Ibarrondo, F Javier, Kickhoefer, Valerie A, Maynard, Heather D, Mrazek, Jan, Rome, Leonard H, Tamshen, Kyle, Wollenberg, Alexander L, Yang, Otto O   +11 more
core  

2519

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: To establish an in vitro quantitative method for the evaluation of polymeric film disintegration that can be applied to predict in vivo behavior.
Sheila Grab, Yvonne Cosgrove Sweeney, Dorothy L. Patton, Lisa C. Rohan   +3 more
doaj   +1 more source

Oral pre‐exposure prophylaxis initiation, continuation and adherence among pregnant and postpartum women receiving antenatal and postnatal care: a systematic review

Journal of the International AIDS Society, Volume 28, Issue S5, September 2025.
Abstract Introduction In 2023, one‐fourth of new HIV acquisitions in children globally resulted from vertical transmission following incident HIV during pregnancy or breastfeeding. Oral pre‐exposure prophylaxis (PrEP) with tenofovir disoproxil and emtricitabine is safe and effective in pregnancy and postpartum, with long‐acting options emerging ...
Anke Rotsaert, Zaynab Essack, Shannon Bosman, Dvora Joseph Davey, Bernadette Hensen   +4 more
wiley   +1 more source

The impact of an educational intervention on undergraduate students’ knowledge, acceptability, and willingness to pay for dapivirine vaginal ring in Nigeria's first indigenous university: a single-arm, non-randomized study

Discover Social Science and Health
Background This study aimed to assess the impact of an educational intervention on knowledge, acceptability, and willingness to pay (WTP) for dapivirine vaginal ring (DPV-VR) by undergraduate female students at the University of Nigeria (UNN).
Abdulmuminu Isah, Gabriel Ezenri, Ogechi Obi, Nnamdi A. Okibe, Hadiza Usman Ma’aji, Ezinwanne J. Ugochukwu, Cynthia C. Eze, Chisom M. Amoke, Augustus Ezeodimegwu, Charles C. Idabor, Mustapha Muhammed Abubakar, Francis Iloabuchi, Ikenna John Ugwu, Chukwuebuka M. Asogwa, Chinwe V. Ukwe, Blessing Onyinye Ukoha-kalu   +15 more
doaj   +1 more source

Density Mediated Drug Release From Dapivirine Vaginal Rings Produced by Additive Manufacturing [PDF]

, 2018
Background: Droplet deposition modelling (DDM) is a form of 3D printing that fuses droplets of molten polymer to create each layer, providing exquisite levels of control over an object‘s design and morphology.
Boyd, Peter, Devlin, Brid, Malcolm, Robert, McCoy, Clare F., Murphy, Diarmaid, Welsh, Nicole   +5 more
core  

“Male-supported, female-initiated”

Communicare, 2022
HIV and AIDS remain one of the leading public health challenges in the world, with young women in sub-Saharan Africa bearing the brunt of HIV infection.
Eliza Govender, Yonela Vukapi, Phiwe Nota   +2 more
doaj   +1 more source

Characterization of porous, dexamethasone-releasing polyurethane coatings for glucose sensors. [PDF]

, 2014
Commercially available implantable needle-type glucose sensors for diabetes management are robust analytically but can be unreliable clinically primarily due to tissue-sensor interactions.
Klitzman, Bruce, Reichert, William M, Vallejo-Heligon, Suzana G   +2 more
core   +1 more source

Estimated impact of long‐acting injectable PrEP in South Africa: a model comparison analysis

Journal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Abstract Introduction Long‐acting injectable cabotegravir (CAB‐LA) demonstrated superiority to daily tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for human immunodeficiency virus (HIV) pre‐exposure prophylaxis (PrEP) in two clinical trials. This analysis projects the impact of expanding PrEP coverage with CAB‐LA in South Africa between 2022 ...
Sarah E. Stansfield, Mia Moore, Lise Jamieson, Gesine Meyer‐Rath, Leigh F. Johnson, David Kaftan, Anna Bershteyn, Jennifer Smith, Valentina Cambiano, Loveleen Bansi‐Matharu, Andrew Phillips, Jesse Heitner, Ruanne V. Barnabas, Brett Hanscom, Deborah J. Donnell, Marie‐Claude Boily, Dobromir Dimitrov   +16 more
wiley   +1 more source

Rationale and safety assessment of a novel intravaginal drug-delivery system with sustained DL-lactic acid release, intended for long-term protection of the vaginal microbiome [PDF]

, 2016
Bacterial vaginosis is a prevalent state of dysbiosis of the vaginal microbiota with wide-ranging impact on human reproductive health. Based on recent insights in community ecology of the vaginal microbiome, we hypothesize that sustained vaginal DL ...
Remon, Jean Paul, Verstraelen, Hans, Vervaet, Chris   +2 more
core   +7 more sources

A model of HIV/AIDS population dynamics including ARV treatment and pre-exposure prophylaxis [PDF]

, 2018
Antiretroviral treatment (ART) and oral pre-exposure prophylaxis (PrEP) have recently been used efficiently in management of HIV infection. Pre-exposure prophylaxis consists in the use of an antiretroviral medication to prevent the acquisition of HIV ...
CP Bhunu, D Kerrigan, EF Drabo, EJ Arts, F Nyabadza, H Grant, JM Baeten, JM Hyman, Joint United Nations Programme on HIV/AIDS, L Hassan, Mozart U Nsuami, P Driessche van den, Peter J Witbooi, R Eakle, RM Anderson, SANA Council, SD Hove-Musekwa, World Health Organization, Z Mukandavire   +18 more
core   +2 more sources