Results 111 to 120 of about 1,978 (184)

Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir

European Journal of Pharmaceutical Sciences, 2010
Dual segment polyurethane intravaginal rings (IVRs) were fabricated to enable sustained release of antiretroviral agents dapivirine and tenofovir to prevent the male to female sexual transmission of the human immunodeficiency virus. Due to the contrasting hydrophilicity of the two drugs, dapivirine and tenofovir were separately formulated into polymers
Todd J, Johnson, Kavita M, Gupta, Judit, Fabian, Theodore H, Albright, Patrick F, Kiser   +4 more
openaire   +2 more sources

Associations between intravaginal practices and incidence of sexually transmitted infections and bacterial vaginosis among women enrolled in the dapivirine vaginal ring trial (The Ring Study) in southwestern Uganda: a retrospective secondary analysis

BMJ Open
Objectives We assessed associations between intravaginal practices (IVPs) and the incidence of sexually transmitted infections (STIs) and bacterial vaginosis (BV) among women using the dapivirine vaginal ring (DVR) or placebo vaginal ring in southwestern
Andrew Abaasa, Eugene Ruzagira, Sylvia Kusemererwa, Anita Kabarambi, Martin Onyango   +4 more
doaj   +1 more source

Integration of a Relationship-focused Counseling Intervention with Delivery of the Dapivirine Ring for HIV Prevention to Women in Johannesburg: Results of the CHARISMA Pilot Study. [PDF]

AIDS Behav, 2022
Montgomery ET, Roberts ST, Reddy K, Tolley E, Hartmann M, Wilson E, Mathebula F, Wagner LD, Zissette S, Lanham M, Wilcher R, Baeten JM, Palanee-Phillips T.   +12 more
europepmc   +1 more source

Anti-Retroviral–Based HIV Pre-Exposure Prophylaxis for Women: Recent Advances and Next Steps [PDF]

, 2017
There is a daunting challenge to prevent human immunodeficiency virus (HIV) acquisition in women at high risk of acquiring HIV. Of the 37 million people globally living with HIV, more than half are women.
Kiweewa, Flavia Matovu, Kiweewa, Francis, Mugwanya, Kenneth K.   +2 more
core   +1 more source

Qualitative focus group discussions exploring PrEP method and service delivery preferences among female sex workers and their managers in four Zambian provinces

BMJ Public Health
Objectives To describe the experiences of oral HIV pre-exposure prophylaxis (PrEP) use, preferences comparing oral PrEP to future long-acting PrEP products (the dapivirine vaginal ring (PrEP ring) and injectable cabotegravir (CAB PrEP)), and service ...
Holly M Burke, Emily Evens, Tendai Munthali, Featherstone Mangunje, Mercy L Kotaka, Bupe Musonda, Musonda Musonda, Catherine S Todd   +7 more
doaj   +1 more source

Client-Centered Adherence Counseling with Adherence Measurement Feedback to Support Use of the Dapivirine Ring in MTN-025 (The HOPE Study). [PDF]

AIDS Behav, 2021
Balán IC, Giguere R, Lentz C, Kutner BA, Kajura-Manyindo C, Byogero R, Asiimwe FB, Makala Y, Jambaya J, Khanyile N, Chetty D, Soto-Torres L, Mayo A, Mgodi NM, Palanee-Phillips T, Baeten JM.   +15 more
europepmc   +1 more source

Comparative efficacy of topical microbicides in the prevention of HIV transmission – results from a systematic review and network meta-analysis [PDF]

Introduction and aim. Preventing new HIV infections is crucial, particularly for women and girls at high risk. Vaginal microbi cides offer a female-controlled HIV prevention method.
Kumar, Suresh, Lee, E Lyn, Noreen, Nabeela, Shanmugham, Suresh, Smales, Frederick Charles, Veettil, Sajesh K.   +5 more
core   +2 more sources

Assessing Per-Sex-Act HIV-1 Risk Reduction Among Women Using the Dapivirine Vaginal Ring. [PDF]

J Infect Dis, 2023
Abstract Background Confounding introduced by individuals’ sexual risk behavior is potentially a significant source of bias in HIV-1 prevention intervention studies. To more completely account for sexual behaviors when assessing the efficacy of the monthly dapivirine ring, a new longer-acting HIV-1 ...
Stalter RM, Dong TQ, Hendrix CW, Palanee-Phillips T, van der Straten A, Hillier SL, Kiweewa FM, Mgodi NM, Marzinke MA, Bekker LG, Soto-Torres L, Baeten JM, Brown ER, MTN-020/ASPIRE Study Team.   +13 more
europepmc   +3 more sources

Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: a systematic review and meta-analysis [PDF]

Background: The World Health Organization (WHO) recommends tenofovir disoproxil fumarate (TDF)-based oral pre-exposure prophylaxis (PrEP), the dapivirine vaginal ring, and long-acting intramuscular injectable cabotegravir (CAB-LA) for HIV prevention in ...
Erlwanger, Alison, Hemelaar, Joris, Kirtley, Shona, Rocroi, Isabelle   +3 more
core   +2 more sources

Lessons learnt from daily oral PrEP delivery to inform national planning for PrEP ring introduction for women in low-income and middle-income countries: a qualitative inquiry of international stakeholders

BMJ Global Health
Introduction Some African countries plan to introduce and scale-up new long-acting pre-exposure prophylaxis methods (LA-PrEP), like the monthly dapivirine vaginal ring (PrEP ring) and injectable cabotegravir.
Sergio Torres-Rueda, Magdalena E Sobieszczyk, Delivette Castor, Craig J Heck, Anita Dam, Kibret Yohannes, Justine Deacon, Katharine Kripke, Kathrine Meyers, Christopher Obermeyer, Sarah Wiant, Daniela Quigee, Martha Larson, Christine Malati, Ohemaa Poku   +14 more
doaj   +1 more source