Results 91 to 100 of about 1,978 (184)

Transforming PrEP marketing: understanding the place of PrEP in the hearts and minds of adolescent girls and young women in sub‐Saharan Africa

open access: yesJournal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Abstract Introduction Adolescent girls and young women (AGYW) in sub‐Saharan Africa (SSA) remain one of the populations most affected by HIV. As HIV prevention options expand—such as the introduction of the dapivirine ring, long‐acting injectable cabotegravir and other potential long‐acting methods—alongside oral pre‐exposure prophylaxis (PrEP), AGYW ...
Emily de Lacy Donaldson   +5 more
wiley   +1 more source

CCR5 antagonists used as topical microbicides modulate CCR5 expression and may potentially compound HIV infection [PDF]

open access: yes, 2017
CCR5 antagonists, such as Maraviroc (MVC) and 5P12-RANTES, are being evaluated as HIV preventatives. The advantage of these drugs is that they restrict HIV entry via CCR5 receptor.
Laux, Julie
core  

Coming of age? Women's sexual and reproductive health after twenty-one years of democracy in South Africa [PDF]

open access: yes, 2016
This paper is a sequel to a 2004 article thet reviewed South Africa's introduction of new sexual and reproductive health (SRH) and rights, laws, policies and programmes, a decade into democracy. Similarly to the previous article this paper focuses on key
Constant, D.   +7 more
core   +1 more source

First Impressions Matter: How Initial Worries Influence Adherence to the Dapivirine Vaginal Ring

open access: yesJAIDS Journal of Acquired Immune Deficiency Syndromes, 2019
Background: In MTN-020/ASPIRE, a dapivirine vaginal ring effectiveness trial in sub-Saharan Africa, we assessed whether worries about ring use changed over time and were associated with adherence. Methods: Participants (N = 2585) were surveyed at baseline and follow-up about worries
Ariane, van der Straten   +9 more
openaire   +3 more sources

Attitudes and perceptions towards novel objective measures of ARV-based vaginal ring use: Results from a global stakeholder survey.

open access: yesPLoS ONE, 2017
Results of recent microbicide and pre-exposure prophylaxis clinical trials have shown adherence to be a significant challenge with new HIV prevention technologies.
Randy M Stalter   +7 more
doaj   +1 more source

Seizing the moment: the potential of PrEP choice and innovation to transform HIV prevention

open access: yesJournal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Abstract Introduction The potential of pre‐exposure prophylaxis (PrEP), as a highly effective and empowering HIV prevention intervention, has not yet been realized. Despite the recent acceleration in the scale‐up of oral PrEP, there is a substantial unmet PrEP need, and the world is not on track to meet the 2025 prevention targets.
Heather‐Marie A. Schmidt   +6 more
wiley   +1 more source

Advancing the use of Long‐Acting Extended Delivery formulations for HIV prevention in sub‐Saharan Africa: challenges, opportunities, and recommendations

open access: yesJournal of the International AIDS Society, 2023
Introduction The burden of HIV in sub‐Saharan Africa (SSA) remains unacceptably high, and disproportionately affects girls and women. While the introduction of oral HIV pre‐exposure prophylaxis (PrEP) in 2012 revolutionized HIV prevention, its ...
Nyaradzo M. Mgodi   +6 more
doaj   +1 more source

The Medical Research Council (UK)/Uganda Virus Research Institute Uganda Research Unit on AIDS--'25 years of research through partnerships'. [PDF]

open access: yes, 2014
For the past 25 years, the Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS has conducted research on HIV-1, coinfections and, more recently, on non-communicable diseases.
Elliott, AM   +4 more
core   +1 more source

2016 Pipeline Report HIV and TB [PDF]

open access: yes, 2016
HIV and TB: Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in ...
Erica Lessem   +7 more
core  

Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors

open access: yesViruses, 2014
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are widely used to treat HIV-1-infected individuals; indeed most first-line antiretroviral therapies typically include one NNRTI in combination with two nucleoside analogs.
Nicolas Sluis-Cremer
doaj   +1 more source

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