Results 51 to 60 of about 148 (100)

Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. [PDF]

Front Mol Biosci, 2022
Frey KM, Bertoletti N, Chan AH, Ippolito JA, Bollini M, Spasov KA, Jorgensen WL, Anderson KS.   +7 more
europepmc   +1 more source

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach. [PDF]

Molecules, 2023
Mansouri M, Rumrill S, Dawson S, Johnson A, Pinson JA, Gunzburg MJ, Latham CF, Barlow N, Mbogo GW, Ellenberg P, Headey SJ, Sluis-Cremer N, Tyssen D, Bauman JD, Ruiz FX, Arnold E, Chalmers DK, Tachedjian G.   +17 more
europepmc   +1 more source

Structural biology of HIV-1 reverse transcriptase allosteric inhibitors for drug design. [PDF]

Acta Pharm Sin B
Zhou Z, Sun Y, Feng D, Wang Z, Zhao F, Gao S, Zhan P, Kang D, Liu X.   +8 more
europepmc   +1 more source

In silico Design of Novel HIV-1 NNRTIs Based on Combined Modeling Studies of Dihydrofuro[3,4-d]pyrimidines. [PDF]

Front Chem, 2020
Chen Y, Tian Y, Gao Y, Wu F, Luo X, Ju X, Liu G.   +6 more
europepmc   +1 more source

Thienopyrimidine: A Promising Scaffold to Access Anti-Infective Agents. [PDF]

Pharmaceuticals (Basel), 2021
Lagardère P, Fersing C, Masurier N, Lisowski V.   +3 more
europepmc   +1 more source

Bioisosterism-driven design of orally active, safe, and broad-spectrum biphenyl-DAPY derivatives as highly potent HIV-1 non-nucleoside reverse transcriptase inhibitors. [PDF]

Acta Pharm Sin B
Chen XM, Hao QQ, Pannecouque C, De Clercq E, Wang S, Chen FE.   +5 more
europepmc   +1 more source

The Meandrous Route of Rilpivirine in the Search for the Miraculous Drug to Treat HIV Infections. [PDF]

Viruses
De Clercq E.
europepmc   +1 more source

Pyrimidine-based NNRTIs in HIV therapy: advances in synthesis, potency and structure-activity relationships. [PDF]

RSC Adv
Ali H, Hashmi MA, Ajmal N, Goraija MS, Rasool N, Siddiqua UH, Malik A.   +6 more
europepmc   +1 more source

Biphenyl as a Privileged Structure in Medicinal Chemistry: Advances in Anti-Infective Drug Discovery. [PDF]

Molecules
Gandi MO, França RRF, Castelo-Branco FS, Boechat N.   +3 more
europepmc   +1 more source

In silico studies of diarylpyridine derivatives as novel HIV-1 NNRTIs using docking-based 3D-QSAR, molecular dynamics, and pharmacophore modeling approaches. [PDF]

RSC Adv, 2018
Wan Y, Tian Y, Wang W, Gu S, Ju X, Liu G.   +5 more
europepmc   +1 more source