Results 81 to 90 of about 727,398 (339)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Effect of Visual Feedback on the Eye Position Stability of Patients with AMD

open access: yesVision, 2019
The sources of the reduced fixation stability exhibited by patients with central vision loss in the light are relatively well understood, but we have no information on how they control eye position in complete darkness, in the absence of visual error ...
Esther G. González   +3 more
doaj   +1 more source

Magnetized LambdaCDM inhomogeneities and the cosmic dark ages

open access: yes, 2011
Exact solutions of the perturbations equations in the magnetized LambdaCDM scenario are presented. They apply during the dark ages and, more specifically, after the baryons are freed from the drag of the photons.
Giovannini, Massimo
core  

The Spin-Resolved Atomic Velocity Distribution and 21-cm Line Profile of Dark-Age Gas

open access: yes, 2006
The 21-cm hyperfine line of atomic hydrogen (HI) is a promising probe of the cosmic dark ages. In past treatments of 21-cm radiation it was assumed the hyperfine level populations of HI could be characterized by a velocity-independent ``spin temperature''
Allison   +46 more
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

‘Transmigrasi Ilmu’: Dari Dunia Islam ke Eropa

open access: yesTsaqafah, 2010
It has been a sad fact that whilst the ancient Greco-Roman civilization and the so-called Renaissance have always received high praise, the period in between, popularly known as the Dark Ages, is highly obscured or just ignored.
Syamsuddin Arif
doaj   +1 more source

Multiple Gaps in the Disk of the Class I Protostar GY 91

open access: yes, 2018
We present the highest spatial resolution ALMA observations to date of the Class I protostar GY 91 in the $\rho$ Ophiuchus L1688 molecular cloud complex.
Eisner, Josh, Sheehan, Patrick
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Steering in the digital dark ages: shall we succeed to preserve our written digital heritage?

open access: yesKnjižnica, 2007
The article deals with the problem of long-term preservation of electronic resources. A brief overview of the practice in this field worldwide as well as in the National and University Library of Slovenia is given.
Alenka Kavčič-Čolić
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

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