Results 71 to 80 of about 2,442,143 (290)
Dark Current Evolution in Irradiated MWIR HgCdTe Photodiodes
HgCdTe detectors are a key technology for space-based infrared imagery. Radiation in the space environment afects the performance of these detectors. Gamma and protons irradiation are performed in order to assess the impact of total ionising dose and displacement damage dose on the dark current of mid-wavelength infrared HgCdTe photodiodes.
Dinand, S +7 more
openaire +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Silicon four element p-i-n photodiode with improved characteristics
This article presents the results of the development of silicon coordinate p-i-n photodiodes (PD) with improved parameters. The technological possibilities of reducing the gaps between the responsive areas of multi-element PDs were studied.
Mykola Kukurudziak
doaj +1 more source
Low dark current N structure superlattice MWIR photodetectors [PDF]
Commercially available read out integrated circuits (ROICs) require the FPA to have high dynamic resistance area product at zero bias (R0A) which is directly related to dark current of the detector. Dark current arises from bulk and surface contributions.
Salihoglu, Omer +4 more
openaire +3 more sources
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Capture and Indirect Detection of Inelastic Dark Matter
We compute the capture rate for Dark Matter in the Sun for models where the dominant interaction with nuclei is inelastic -- the Dark Matter up-scatters to a nearby dark "partner" state with a small splitting of order a 100 keV.
Menon, Arjun +3 more
core +1 more source
Dark Current Studies for SwissFEL
Activation of the surroundings of an accelerator must be quantified and those data provided to the official agencies. This is a necessary step in obtaining the authorization to operate such an accelerator. SwissFEL, being a fourth generation light source, will produce more accelerated charges, which are dumped or lost, than conventional third ...
Pimpec, F. Le +6 more
openaire +2 more sources
Current status of direct dark matter detection experiments [PDF]
6 pages, 4 figures, version accepted by Nature ...
Jianglai Liu, Xun Chen, Xiangdong Ji
openaire +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

