Results 41 to 50 of about 111,737 (267)

Baryonic distributions in the dark matter halo of NGC 5005 [PDF]

Monthly Notices of the Royal Astronomical Society, 2015
We present results from multiwavelength observations of the galaxy NGC5005. We use new neutral hydrogen (HI) observations from the Very Large Array to examine the neutral gas morphology and kinematics. We find an HI disk with a well-behaved flat rotation curve in the radial range 20\arcsec-140\arcsec.
Richards, Emily E., van Zee, L., Barnes, K. L., Staudaher, S., Dale, D. A., Braun, T. T., Wavle, D. C., Calzetti, D., Dalcanton, J. J., Bullock, J. S., Chandar, R.   +10 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The DREAMS Project: Disentangling the Impact of Halo-to-halo Variance and Baryonic Feedback on Milky Way Dark Matter Density Profiles

The Astrophysical Journal
In this work, we utilize a new suite of Milky Way–mass halos from the DREAMS Project, simulated with cold dark matter (CDM), to quantify the influence of baryon feedback and intrinsic halo-to-halo variance on dark matter density profiles.
Alex M. Garcia, Jonah C. Rose, Paul Torrey, Andrea Caputo, Mariangela Lisanti, Andrew B. Pace, Hongwan Liu, Abdelaziz Hussein, Haozhe Liu, Francisco Villaescusa-Navarro, John Barry, Ilem Leisher, Belén Costanza, Jonathan Kho, Ethan Lilie, Jiaxuan Li, Niusha Ahvazi, Aklant Bhowmick, Tri Nguyen, Stephanie O’Neil, Xiaowei Ou, Xuejian Shen, Arya Farahi, Nitya Kallivayalil, Lina Necib, Mark Vogelsberger   +25 more
doaj   +1 more source

The AIDA-TNG project: Abundance, radial distribution, and clustering properties of halos in alternative dark matter models

Astronomy & Astrophysics
Warm and self-interactive dark matter cosmologies have been proposed as nonbaryonic solutions to the tensions between the Λ cold dark matter model and observations at the kiloparsec scale.
Romanello M., Despali G., Marulli F., Giocoli C., Moscardini L., Vogelsberger M.   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The DREAMS Project: Disentangling the Impact of Halo-to-Halo Variance and Baryonic Feedback on Milky Way Dark Matter Speed Distributions

The Astrophysical Journal
Dark matter direct detection experiments require information about the local dark matter speed distribution to produce constraints on dark matter candidates, or infer their properties in the event of a discovery.
Ethan Lilie, Jonah C. Rose, Mariangela Lisanti, Alex M. Garcia, Paul Torrey, Kassidy E. Kollmann, Jiaxuan Li, Olivia Mostow, Bonny Y. Wang, Stephanie O’Neil, Xuejian Shen, Alyson M. Brooks, Arya Farahi, Nitya Kallivayalil, Lina Necib, Andrew B. Pace, Mark Vogelsberger   +16 more
doaj   +1 more source

Stationar spherical-symmetric configuration of dark matter

Physical Sciences and Technology, 2021
The article is devoted to the consideration of a model problem, where mass flow of dark matter which take as only gravitational interacting spherical continuous medium without pressure and with radial opposite motion with equilibrium ascending and ...
M. Abishev, N. Beissen, B. Karsimanov, I. Uspanov, M. O. Alimkulova   +4 more
doaj   +1 more source

Dark Matter Distribution in Nearby Galaxies [PDF]

Symposium - International Astronomical Union, 2004
We present results obtained from a study of the mass distribution of 24 galaxies observed using Fabry-Pérot techniques, as part of the GHASP survey (see Russeil et al., this meeting). For each galaxy, we combined high resolution Hα rotation curves derived from 2-D velocity fields, with low resolution HI data, in order to determine accurately the inner ...
Olivia Garrido, Philippe Amram, Claude Carignan, Sébastien Blais-Ouellette, Michel Marcelin, Delphine Russeil   +5 more
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Roman View of Strong Gravitational Lenses

The Astrophysical Journal
Galaxy–galaxy strong gravitational lenses can constrain dark matter models and the Lambda cold dark matter cosmological paradigm at subgalactic scales. Currently, there is a dearth of images of these rare systems with high signal-to-noise ratio (SNR) and
Bryce Wedig, Tansu Daylan, Simon Birrer, Francis-Yan Cyr-Racine, Cora Dvorkin, Douglas P. Finkbeiner, Alan Huang, Xiaosheng Huang, Rahul Karthik, Narayan Khadka, Priyamvada Natarajan, Anna M. Nierenberg, Annika H. G. Peter, Justin D. R. Pierel, Xianzhe TZ Tang, Risa H. Wechsler   +15 more
doaj   +1 more source