Results 61 to 70 of about 111,737 (267)

Negative Matter as Unified Dark Matter and Dark Energy, Distributions of Dark Matter-Energy, and Observed Ways in the Milky Way

open access: yesEuropean Journal of Theoretical and Applied Sciences, 2023
There are not necessarily dark matter and dark energy in the solar system, and dark energy cannot distribute uniformly in the whole space. Based on Dirac negative energy, Einstein mass-energy relation and principle of equivalence, we proposed the negative matter as the simplest model of unified dark matter and dark energy.
openaire   +2 more sources

The Distribution of Dark Matter in a Ringed Galaxy [PDF]

open access: yesThe Astrophysical Journal, 1997
AAS Latex + jpg Figures, Accepted for publication in ...
Quillen, A. C., Frogel, J. A.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

How to Build an Empirical Speed Distribution for Dark Matter in the Solar Neighborhood

open access: yesThe Astrophysical Journal
The dark matter flux in a direct detection experiment depends on its local speed distribution. This distribution has been inferred from simulations of Milky Way–like galaxies, but such models serve only as proxies, given that no simulation directly ...
Tal Shpigel   +5 more
doaj   +1 more source

Caustics, Cold Flows, and Annual Modulation

open access: yesAdvances in Astronomy, 2011
We discuss the formation of dark matter caustics, and their possible detection by future dark matter experiments. The annual modulation expected in the recoil rate measured by a dark matter detector is discussed.
Aravind Natarajan
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Spatial Distribution of Intracluster Light versus Dark Matter in Horizon Run 5

open access: yesThe Astrophysical Journal
One intriguing approach for studying the dynamical evolution of galaxy clusters is to compare the spatial distributions among various components such as dark matter, member galaxies, gas, and intracluster light (ICL).
Jaewon Yoo   +13 more
doaj   +1 more source

Dark Matter: A Primer

open access: yesAdvances in Astronomy, 2011
Dark matter is one of the greatest unsolved mysteries in cosmology at the present time. About 80% of the Universe's gravitating matter is nonluminous, and its nature and distribution are for the most part unknown.
Katherine Garrett, Gintaras Duda
doaj   +1 more source

Collider Searches for Dark Matter (ATLAS + CMS)

open access: yesUniverse, 2018
Several searches for dark matter have been performed by the CMS and ATLAS collaborations, using proton-proton collisions with a center-of-mass energy of 13 TeV produced by the Large Hadron Collider. Different signatures may highlight the presence of dark
Nicolò Trevisani
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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