Results 81 to 90 of about 111,737 (267)

Distribution of dark matter in the spiral galaxy NGC 3198

The Astrophysical Journal, 1985
Two-component mass models, consisting of an exponential disk and a spherical halo, are constructed to fit a newly determined rotation curve of NGC 3198 that extends to 11 disk scale lengths. The amount of dark matter inside the last point of the rotation curve, at 30 kpc, is at least 4 times larger than the amount of visible matter, with M/L(B)tot = 18
VANALBADA, TS, BAHCALL, JN, BEGEMAN, K, SANSCISI, R   +3 more
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dark Matter Signals in the gamma-ray sky

EPJ Web of Conferences, 2014
Detection of gamma rays and cosmic rays from the annihilation or decay of dark matter particles is a promising method for identifying dark matter, understanding its intrinsic properties, and mapping its distribution in the universe.
Morselli Aldo
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

MrMARTIAN: A Multiresolution Mass Reconstruction Algorithm Combining Free-form and Analytic Components

The Astrophysical Journal
We present Multi-resolution MAximum-entropy Reconstruction Technique Integrating Analytic Node ( MrMARTIAN ), a new hybrid strong lensing (SL) modeling algorithm.
Sangjun Cha, M. James Jee
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Probing multicomponent extension of inert doublet model with a vector dark matter

European Physical Journal C: Particles and Fields, 2019
Although theoretically well-motivated as a minimal consistent dark matter (DM) model, the inert doublet model (IDM) fell short in explaining the existence of DM in the intermediate mass region (100–500 GeV).
Sreemanti Chakraborti, Amit Dutta Banik, Rashidul Islam   +2 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Particle dark matter searches in the anisotropic sky

Frontiers in Physics, 2014
Anisotropies in the electromagnetic emission produced by dark matter annihilation or decay in the extragalactic sky are a recent tool in the quest for a particle dark matter evidence.
Nicolao eFornengo, Nicolao eFornengo, Marco eRegis, Marco eRegis   +3 more
doaj   +1 more source