Results 91 to 100 of about 4,043,825 (280)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Assessing Dark Patterns in Mindfulness Applications [PDF]

open access: yes
openMindfulness applications are on the rise of popularity and are becoming a promising business. The applications promise to users that if they engage with the app, their stress and problems will be at ease.
NGUYEN, THU PHUONG
core  

Dark patterns detection in e-commerce websites. [PDF]

open access: yes, 2022
To get the most out of users, website owners often decide to use dark patterns in the design of their systems. Dark patterns – user interface that was carefully created to deceive the user into giving more information or buying more goods than intended ...
Anužas, Paulius,
core  

Leveraging interdisciplinary methods for evidence collection in enforcement: Dark patterns as a case study

open access: yesInternet Policy Review
“Dark patterns” are manipulative, deceptive design practices deployed in online services to influence users’ decisions towards undesired or negative outcomes.
Johanna Gunawan   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Dark patterns: the black holes on the web

open access: yes, 2023
reservedPartendo dalla relazione dell'OECD del 2020, l'elaborato presenta i dark patterns nella loro complessità. Analizza le loro diverse tipologie corredate da esempi pratici.
FASOLO, ELIA
core  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Dark patterns and consumer behaviour

open access: yes
Survey data on dark patterns and consumer ...
Soliman, Mohammad
core   +1 more source

Dark Carbon Fixation Measurements in the East Sea (Sea of Japan)

open access: yesJournal of Marine Science and Engineering
The vertical distribution patterns of daily primary production and dark carbon fixation were investigated at three stations in the East/Japan Sea (hereafter East Sea), a semi-enclosed marginal sea in the northwest Pacific Ocean.
Hyo-Keun Jang   +10 more
doaj   +1 more source

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