Results 91 to 100 of about 3,890,266 (282)
Internet Policy Review“Dark patterns” are manipulative, deceptive design practices deployed in online services to influence users’ decisions towards undesired or negative outcomes.
Johanna Gunawan +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A Comprehensive Study on Dark Patterns
CoRRAs digital interfaces become increasingly prevalent, certain manipulative design elements have emerged that may harm user interests, raising associated ethical concerns and bringing dark patterns into focus as a significant research topic. Manipulative design strategies are widely used in user interfaces (UI) primarily to guide user behavior in ways ...
Meng Li 0006 +7 more
openaire +3 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Dark patterns in persuasive computing. [PDF]
, 2022 Dark patterns are user interface patterns that, by exploiting the psychological features of attracting and retaining attention, force consumers to make decisions that benefit service providers and ensure business profitability.
Tarasenka, Artūras,
core
Dark Carbon Fixation Measurements in the East Sea (Sea of Japan)
Journal of Marine Science and EngineeringThe vertical distribution patterns of daily primary production and dark carbon fixation were investigated at three stations in the East/Japan Sea (hereafter East Sea), a semi-enclosed marginal sea in the northwest Pacific Ocean.
Hyo-Keun Jang +10 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Assessing Dark Patterns in Mindfulness Applications [PDF]
openMindfulness applications are on the rise of popularity and are becoming a promising business. The applications promise to users that if they engage with the app, their stress and problems will be at ease.
NGUYEN, THU PHUONG
core
La manipolazione occulta: come i dark patterns influenzano le decisioni dei consumatori [PDF]
Democrazia e Diritti SocialiIncreasing competition in sales has led retailers to adopt different strategies to engage users and guide them through the digital purchasing process. Some retailers use ‘digital nudges’ that aim to guide the user through the buying process.
Fabrizio Corona
doaj