Results 71 to 80 of about 50,717 (262)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Research Progress on Microbial Diversity and Its Functional Activities during Pile Fermentation of Dark Tea

Shipin gongye ke-ji
Dark tea is a type of post-fermented tea with unique sensory characteristics. The tea product is usually obtained in the four steps, namely fixation, rolling, pile fermentation, and drying.
Jiaru WEI, Kaili NIE, Xiaoqiang CHEN, Miaomiao YING   +3 more
doaj   +1 more source

Dark tea extracts: Chemical constituents and modulatory effect on gastrointestinal function

Biomedicine & Pharmacotherapy, 2020
Processing of dark tea varieties, such as Fu brick tea, Liupao tea, Qianliang tea, and Qing brick tea, includes solid-state fermentation involving microorganisms. In this study, we analyzed the major chemical constituents of dark tea extracts and evaluated their modulatory effect on the gastrointestinal function in normal mice, including the ...
Zhi-Ping, Gong, Jian, Ouyang, Xiang-Lan, Wu, Fang, Zhou, Dan-Ming, Lu, Chen-Jie, Zhao, Chun-Fang, Liu, Wan, Zhu, Jing-Chi, Zhang, Neng-Xin, Li, Feng, Miao, Yu-Xin, Song, Yi-Long, Li, Qi-Ye, Wang, Hai-Yan, Lin, Xin, Zeng, Shu-Xian, Cai, Jian-An, Huang, Zhong-Hua, Liu, Ming-Zhi, Zhu   +19 more
openaire   +2 more sources

Complete mitochondrial genome and phylogenetic analysis of Penicillium citrinum in dark tea [PDF]

Mitochondrial DNA Part B, 2019
Penicillium citrinum is a common polluting microorganism in dark tea production. Our study was performed to report the complete mitochondrial genome of P. citrinum. The mitochondrial genome of P. citrinum was a circular DNA molecule of 27,537 bp in length, encoding 42 genes as follows: 15 PCGs, two rRNAs, 24 tRNAs, and an independent ORF. A (36.14%), T
Zhiyuan Hu, Liu Shiquan, Zhenggang Xu, Meng Dong, Suchun Liu   +4 more
openaire   +3 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Multiplex PCR Identification of Aspergillus cristatus and Aspergillus chevalieri in Liupao Tea Based on Orphan Genes

Foods, 2022
“Golden flower” fungi in dark tea are beneficial to human health. The rapid identification method of “golden flower” fungi can verify the quality of dark tea products and ensure food safety. In this study, 6 strains were isolated from Liupao tea.
Zhong Wang, Qifang Jin, Qin Li, Xingchang Ou, Shi Li, Zhonghua Liu, Jian’an Huang   +6 more
doaj   +1 more source

Efficient Electrocatalytic Conversion of CO2 to Pure Formic Acid Solutions via Strain‐Engineered Bismuth Nanosheets

Advanced Science, EarlyView.
Tensile‐strained bismuth nanosheets (TS‐BiNs) achieve a formate Faradaic efficiency of 92% at −1000 mA cm−2 and enable stable production of pure formic acid (HCOOH) in a solid‐state electrolyte reactor. Theoretical calculations reveal that the introduced strain lowers the energy barrier for *OCHO intermediate formation, fundamentally enhancing the ...
Shiqi Li, Yuefeng Zhang, Panzhe Qiao, Cuo Wu, Xinya Tian, Yufeng Xu, Yun Zhang, Peng Wang, Tingting Li, Muhammad Afaq, Xinlin Luo, Tang Wang, Chunxiao Liu, Zi‐You Yu, Chuan Xia, Min‐Rui Gao, Zhen‐Yu Wu   +16 more
wiley   +1 more source

Effects of Raw Materials from Different Tea Cultivars of Leaf Colour on Sichuan Dark Tea Quality

Shipin gongye ke-ji
To explore the influence of raw materials from different cultivars on the quality of Sichuan dark tea, the raw materials of 4 tea cultivars were used in this study.
Yuanyuan XIONG, Ting ZHANG, Xiao LIU, Weiwei MA, Xiaobo TANG, Xiaoping WANG, Yun WANG, Chunhua LI   +7 more
doaj   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

Advanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong, Tuba Marjan, Ngoc Ha Luong, Taimoor H. Qazi, Chien‐Chi Lin   +4 more
wiley   +1 more source