Results 181 to 190 of about 8,310 (209)

Occurrence of DAT1 (VNTR) Polymorphism in Individuals with HIV Infection

Current Pharmacogenomics and Personalized Medicine, 2021
Background: Antiretroviral treatment (ART) has been reported to make changes in the functioning of dopaminergic neurons by altering the expression of dopamine active transporter (DAT). ART containing efavirenz drug has been related to show the adverse reactions on the central nervous system (CNS).
HariOm Singh, Sonam Lata
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Functional Effects of the DAT1 Polymorphism on EEG Measures in ADHD

Journal of the American Academy of Child & Adolescent Psychiatry, 2003
This paper examines whether dopamine transporter gene (DAT1) allele status mediates medication-related change in cognitive and neurophysiological measures among children with attention-deficiency/hyperactivity disorder (ADHD).A single 10-mg dose of methylphenidate was given in a double-blind, placebo-controlled fashion to children with ADHD who were ...
Sandra K, Loo, Elaine, Specter, Andrew, Smolen, Christian, Hopfer, Peter D, Teale, Martin L, Reite   +5 more
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The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression [PDF]

Pharmacogenomics Journal, 2001
The human dopamine transporter (DAT1) gene contains a variable number of tandem repeats (VNTR) in its 3'-untranslated region (UTR). The linkage and association between the VNTR polymorphism of DAT1 and various neuropsychiatric disorders have been reported.
S, Fuke, S, Suo, N, Takahashi, H, Koike, N, Sasagawa, S, Ishiura   +5 more
exaly   +3 more sources

Role of dopamine transporter gene (DAT1) polymorphisms in personality traits variation

Russian Journal of Genetics, 2009
According to psychobiological model of personality proposed by Cloninger, personality traits characterizing enhanced tendency to novel stimuli, impulsivity and sociability are influenced by dopaminergic system functioning. The present study considered both the main effect of two polymorphic loci (VNTR and 2319G>A) in dopamine transporter gene (DAT1 ...
Kazantseva, AV, Khusnutdinova, EK, Gaysina, DA, Malykh, SB   +3 more
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Potential association of DRD2 and DAT1 genetic variation with heroin dependence

Neuroscience Letters, 2009
The aim of our study was to investigate the potential association of dopamine receptor D2 gene (DRD2) TaqI RFLP A (rs1800497) and dopamine transporter gene (DAT) 3'untranslated region VNTR genetic variations with heroin addiction. Genotyping was performed using PCR-based techniques in 530 heroin abusers and 500 controls.
Qiao-Fang, Hou, Sheng-Bin, Li
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DAT1 VNTR allele frequencies in the Omani population.

Human biology, 2005
To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis. Two common alleles (DAT1*9 and DAT1*10) were observed with a frequency of 0.332 and 0.609, respectively. There were also five rare alleles (*3, *6, *7, *8, and *11). The
M, Simsek, K, Lawatia, S, Al-Adawi, M, Al-Sharbati   +3 more
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Relations between multi-informant assessments of ADHD symptoms, DAT1, and DRD4.

Journal of Abnormal Psychology, 2008
Researchers conducting candidate gene studies of attention-deficit/hyperactivity disorder (ADHD) typically obtain symptom ratings from multiple informants (i.e., mothers, fathers, and teachers) and use a psychologist's best estimate or a simple algorithm, such as taking the highest symptom ratings across informants, to construct diagnostic phenotypes ...
Ian R. Gizer, Irwin D. Waldman, Ann Abramowitz, Cathy L. Barr, Yu Feng, Karen G. Wigg, Virginia L. Misener, David C. Rowe   +7 more
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VNTR polymorphism for the human dopamine transporter gene (DAT1)

Human Molecular Genetics, 1993
W, Byerley, M, Hoff, J, Holik, M G, Caron, B, Giros   +4 more
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The Dopamine Transporter Gene (DAT1) in Obesity and Binge Eating Disorders

2011
Reward-based motivations to eat seem to overpower homeostatic drives in some individuals. Binge eating represents an extreme phenotype of hedonic overeating, is a significant risk factor for substantial weight gain over time, and a defining symptom of both binge eating disorder (BED) and bulimia nervosa.
Karen Wight, Caroline Reid-Westoby, Caroline Davis   +2 more
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Cardio-Metabolic and Psychiatric Comorbidities: Early Adversity-DAT1 Gene Network Interactions

Biological Psychiatry, 2022
Barbara Barth, Danusa Mar Arcego, Euclides José de Mendonça Filho, Randriely Merscher de Lima, Sachin Patel, Omar Khedr, Zihan Wang, Carine Parent, Carla Dalmaz, André Krumel Portella, Irina Pokhvisneva, Michael Meaney, Patricia Pelufo Silveira   +12 more
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