Results 101 to 110 of about 3,837,082 (288)

Supervisory Multi Switching Data Driven Control Theory and Application

IEEE Access
Due to the varying circumstances, thus resulting in frequently changed system plant, the controller must also varies with time increases. This paper proposes supervisory multi switching data driven control strategy from both theoretical analysis and ...
Hong Wangjian, Cao Lei
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Data-Driven Model-Free Adaptive Control Based on Error Minimized Regularized Online Sequential Extreme Learning Machine

Energies, 2019
Model-free adaptive control (MFAC) builds a virtual equivalent dynamic linearized model by using a dynamic linearization technique. The virtual equivalent dynamic linearized model contains some time-varying parameters, time-varying parameters usually ...
Xiaofei Zhang, Hongbin Ma
doaj   +1 more source

Data Driven Control of Vagus Nerve Stimulation for the Cardiovascular System: An in Silico Computational Study. [PDF]

Front Physiol, 2022
Branen A, Yao Y, Kothare MV, Mahmoudi B, Kumar G.   +4 more
europepmc   +1 more source

Safe Data-Driven Predictive Control

IEEE Transactions on Automation Science and Engineering
In the realm of control systems, model predictive control (MPC) has exhibited remarkable potential; however, its reliance on accurate models and substantial computational resources has hindered its broader application, especially within real-time nonlinear systems.
Amin Vahidi-Moghaddam, Kaian Chen, Kaixiang Zhang, Zhaojian Li, Yan Wang, Kai Wu   +5 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Data-driven ship trajectory tracking control method

Zhongguo Jianchuan Yanjiu
ObjectiveAiming at the problems of unknown ship model parameters and external disturbance and servo constraints, this paper proposes a method for the data-driven online identification of ship parameters and iterative analytical calculation of the optimal
Yong XIONG, Siwen ZHOU, XianFei WANG, Zhiyuan LYU   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source