Results 181 to 190 of about 34,112,328 (298)

Data is the New Gold: unify and accelerate the path to become a data-driven organization. A TOYOTA case study.

open access: yes
reservedRapid technological developments are redefining what it means to be a data-driven company. Today, organizations are using sporadically Artificial Intelligence (AI) and Business Intelligence (BI) to predict trends and uncover insights, based on ...
BADARAU, ADRIAN
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Predictive Modeling of Acute Hypertensive Disorders in a Real-World Cohort: Integrating Clinical Predictors and Data-Driven Methods. [PDF]

open access: yesDiagnostics (Basel)
Fucile I   +15 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Disentangling Heterogeneity in Alzheimer's Disease and Related Dementias Using Data-Driven Methods. [PDF]

open access: yesBiol Psychiatry, 2020
Habes M   +5 more
europepmc   +1 more source

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