Disentangling Heterogeneity in Alzheimer's Disease and Related Dementias Using Data-Driven Methods. [PDF]
Biol Psychiatry, 2020 Habes M +5 more
europepmc +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Advancing mixed-integer programming using data-driven and deduction-based methods
ADVANCING MIXED-INTEGER PROGRAMMING USING DATA-DRIVEN AND DEDUCTION-BASED METHODS Advancing mixed-integer programming using data-driven and deduction-based methods / Chmiela, Antonia (Rights reserved) (-
Chmiela, Antonia
core
Improved food image recognition by leveraging deep learning and data-driven methods with an application to Central Asian Food Scene. [PDF]
Sci RepKarabay A, Varol HA, Chan MY.
europepmc +1 more source
Data-Driven Methods for the Estimation of Leaf Water and Dry Matter Content: Performances, Potential and Limitations. [PDF]
Sensors (Basel), 2020 Yang B, Lin H, He Y.
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Deep-Neural-Networks-Based Data-Driven Methods for Characterizing the Mechanical Behavior of Hydroxyl-Terminated Polyether Propellants. [PDF]
Polymers (Basel)Han R, Fu X, Qu B, Shi, Liu Y.
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Prediction of craving across studies: A commentary on conceptual and methodological considerations when using data-driven methods. [PDF]
J Behav AddictAntons S +6 more
europepmc +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source