Results 81 to 90 of about 22,699,368 (374)

Party Competition Over Democracy: Democracy as Electoral Issue in Germany

Politics and Governance
Elected leaders increasingly undermine liberal democratic institutions with the support of their voters, openly challenging liberal democratic institutions in election campaigns.
Lea Kaftan
doaj   +1 more source

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals. [PDF]

, 2019
A database of 91 chemicals with published data from both transgenic rodent mutation (TGR) and rodent comet assays has been compiled. The objective was to compare the sensitivity of the two assays for detecting genotoxicity.
Aardema, MJ, Beevers, C, Bhalli, J, Douglas, GR, Escobar, PA, Farabaugh, CS, Guerard, M, Johnson, GE, Kirkland, D, Kulkarni, R, Le Curieux, F, LeBaron, MJ, Levy, DD, Long, AS, Lott, J, Lovell, DP, Luijten, M, Marchetti, F, Nicolette, JJ, Pfuhler, S, Roberts, DJ, Stankowski, LF, Thybaud, V, Weiner, SK, Williams, A, Witt, KL, Young, R   +26 more
core   +3 more sources

Augmented Understanding and Automated Adaptation of Curation Rules [PDF]

arXiv, 2020
Over the past years, there has been many efforts to curate and increase the added value of the raw data. Data curation has been defined as activities and processes an analyst undertakes to transform the raw data into contextualized data and knowledge.
arxiv  

Oasis: Data Curation and Assessment System for Pretraining of Large Language Models [PDF]

arXiv, 2023
Data is one of the most critical elements in building a large language model. However, existing systems either fail to customize a corpus curation pipeline or neglect to leverage comprehensive corpus assessment for iterative optimization of the curation. To this end, we present a pretraining corpus curation and assessment platform called Oasis -- a one-
arxiv  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Reactome - a knowledgebase of human biological pathways [PDF]

, 2007
Pathway curation is a powerful tool for systematically associating gene products with functions. Reactome (www.reactome.org) is a manually curated human pathway knowledgebase describing a wide range of biological processes in a computationally accessible
Bernard de Bono, Bijay Jassal, David Croft, Esther Schmidt, Ewan Birney, Gopal Gopinath, Guanming Wu, Imre Vastrik, Lincoln Stein, Lisa Matthews, Marc Gillespie, Peter D', Suzanna Lewis   +12 more
core   +2 more sources

IRTA Data Curation Checklist for Curators

, 2022
The Data Curation Checklist for curators is a practical guide for data curators to ensure that all datasets submitted to multidisciplinary repositories are consistent to be shared and reproduced following the FAIR practices. This work document follows the data curation best practices from DCN CURATED Steps (produced by Data Curation Network).
Reverté, Carmen, Bonay Giner, Enric
openaire   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

The Data Curation Network: Leveraging Expertise to Curate Data at Scale

, 2019
The Data Curation Network launched the three-year pilot of a distributed model for the curation of research data in 2018. Good curation increases the value and impact of research data. The collaborative, networked approach of the Data Curation Network leverages the expertise across network members to enhance the local repository’s ability to curate ...
Blake, Mara, Herndon, Joel
openaire   +2 more sources

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source