Results 41 to 50 of about 525,062 (261)

A retrospective cohort study to compare post-injury admissions for infectious diseases in burn patients, non-burn trauma patients and uninjured people

Burns & Trauma, 2018
Background Injury triggers a range of systemic effects including inflammation and immune responses. This study aimed to compare infectious disease admissions after burn and other types of injury using linked hospital admissions data.
Janine M. Duke, Sean M. Randall, James H. Boyd, Mark W. Fear, Suzanne Rea, Fiona M. Wood   +5 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Long-term mental health outcomes after unintentional burns sustained during childhood: a retrospective cohort study

Burns & Trauma, 2018
Background Burns are a devastating injury that can cause physical and psychological issues. Limited data exist on long-term mental health (MH) after unintentional burns sustained during childhood.
Janine M. Duke, Sean M. Randall, Thirthar P. Vetrichevvel, Sarah McGarry, James H. Boyd, Suzanne Rea, Fiona M. Wood   +6 more
doaj   +1 more source

A Privacy Attack on Multiple Dynamic Match-key based Privacy-Preserving Record Linkage

International Journal of Population Data Science, 2020
Introduction Over the last decade, the demand for linking records about people across databases has increased in various domains. Privacy challenges associated with linking sensitive information led to the development of privacy-preserving record ...
Anushka Vidanage, Thilina Ranbaduge, Peter Christen, Sean Randall   +3 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

A population-based comparison study of the mental health of patients with intentional and unintentional burns

Burns & Trauma, 2018
Background A number of studies report high prevalence of mental health conditions among burn patients. However there is a need to understand differences in the temporal relationship between mental health conditions and intentional and unintentional burns
Thirthar P Vetrichevvel, Sean M Randall, Fiona M Wood, Suzanne Rea, James H Boyd, Janine M Duke   +5 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Using administrative datasets to improve linkage rates and quality of PII in the Generation Victoria cohort

International Journal of Population Data Science
Maintaining accurate personal identifying information (PII) is a challenge for large population cohorts. Over time, identifier quality declines, reducing linkage sensitivity and increasing false matches and manual clerical review.
Sharon Goldfield, Jatender Mohal, Anthony Del Monaco, Anna Fedyukova, Adam Ismail, Philip Witowski, Adam Moss, Sharon Williams, Melissa Wake   +8 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Data linkage to national Australian health insurance data to investigate exposure to environmental hazards: the example of residential asbestos

International Journal of Population Data Science, 2018
Introduction The enrolment data for Medicare, the Australian universal health insurance provider, covers almost the entire population. Medicare data are commonly used for data linkage, usually to access national medical and pharmaceutical data.
Phil Anderson, Rosemary Korda, Hsei Di Law, Martyn Kirk, Tenniel Guiver   +4 more
doaj   +1 more source