Results 91 to 100 of about 4,706,789 (286)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Corruption and trade protection: evidence from panel data [PDF]
This paper provides new estimates of the effects of corruption and poor institutions on trade protection. It exploits data on several measures of trade protection including import duty, international trade taxes, and the trade-GDP ratio.
Subhayu Bandyopadhyay, Suryadipta Roy
core
European Court of Human Rights : Satakunnan Markkinapörssi Oy and Satamedia Oy v. Finland [PDF]
, 2017 The Grand Chamber judgment of European Court of Human Rights (ECtHR) finds that a prohibition issued by the Finnish Data Protection Board that prohibited two media companies from publishing personal taxation data in the manner and to the extent they had ...
Voorhoof, Dirk
core
CamFlow: Managed Data-sharing for Cloud Services
, 2015 A model of cloud services is emerging whereby a few trusted providers manage the underlying hardware and communications whereas many companies build on this infrastructure to offer higher level, cloud-hosted PaaS services and/or SaaS applications.
Bacon, Jean +3 more
core +2 more sources
Privacy CURE: Consent Comprehension Made Easy [PDF]
, 2020 Although the General Data Protection Regulation (GDPR) defines several potential legal bases for personal data processing, in many cases data controllers, even when they are located outside the European Union (EU), will need to obtain consent from EU ...
Drozd, Olha, Kirrane, Sabrina
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Legal aspects of Big Data - GDPR [PDF]
The use of Big Data presents significant legal problems, especially in terms of data protection. The existing legal framework of the European Union based in particular on the Directive no. 46/95/EC and the General Regulation on the Protection of Personal
Sfetcu, Nicolae
core
An Examination of Privacy Policies of Global University Web Sites [PDF]
, 2011 Due to demand in online services, universities throughout the world are increasing the content of their Web sites and adding features, such as online applications and e-learning.
Kuzma, Joanne
core +1 more source
Analysis of Nuclear Explosion Detection Capability of IMS Hydroacoustic Network
Shock and VibrationThe Comprehensive Nuclear Test Ban Treaty (CTBT) organization has established a hydroacoustic network to ensure the effective detection of nuclear explosions in the vast ocean and in the atmosphere over it in order to effectively guarantee the ...
Yan Wang +5 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source