Results 71 to 80 of about 1,511,903 (267)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Effect of Corrosion Inhibitors on the Corrosion Behavior of Ductile Cast Iron

Metals
Based on actual service environment parameters, this experiment investigated the change in the corrosion rate of nodular cast iron (DCI) in an environment containing organic (triethanolamine phosphate, PTEA) and inorganic (hexametaphosphate, SHMP ...
Jing Liu, Bingqin Wang, Tianqi Chen, Lianjun Hao, Jun Wu, Chao Liu   +5 more
doaj   +1 more source

Corrosion Behavior of Printed Circuit Boards in Tropical Marine Atmosphere

International Journal of Electrochemical Science, 2019
Outdoor exposure experiments of PCB-Cu, PCB-ImAg and PCB-ENIG were conducted in a tropical marine atmosphere under the synergistic effect of multiple factors, and the corresponding corrosion behavior of the PCBs was investigated by SEM, EDS and EIS.
Yali Feng, Ziheng Bai, Qiong Yao, Dongjiu Zhang, Jialiang Song, Chaofang Dong, Junsheng Wu, Kui Xiao   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effect of Cr on the microstructure and corrosion behavior of nickel-based alloys in hydrochloric acid

Journal of Materials Research and Technology
Nickel-base alloy is a type of metal material with excellent properties and is widely used in many fields. However, in the harsh environment of the acid solution, corrosion causes the reduction of the service life of the alloys, thereby limiting the ...
Dianhui Hou, Hong Luo, Zhimin Pan, Qiancheng Zhao, Hongxu Cheng, Xuefei Wang   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Essential role of Si in enhancing corrosion resistance of high strength low alloy steels in marine environment

Journal of Materials Research and Technology
High strength low alloy steels are extensively applied in marine engineering structures (cross-sea bridge, ocean platform, etc), which are usually subjected to severe corrosion in marine atmosphere.
Jinbin Zhao, Pengxin Wang, Hongchi Ma, Xuequn Cheng, Xiaogang Li   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis of Nuclear Explosion Detection Capability of IMS Hydroacoustic Network

Shock and Vibration
The Comprehensive Nuclear Test Ban Treaty (CTBT) organization has established a hydroacoustic network to ensure the effective detection of nuclear explosions in the vast ocean and in the atmosphere over it in order to effectively guarantee the ...
Yan Wang, Wei Tang, Zhehan Liu, Jian Li, Xiaoming Wang, Shiya Zou   +5 more
doaj   +1 more source