Results 111 to 120 of about 13,718,038 (321)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Kaleidoscopic Data Science

open access: yesHarvard Data Science Review, 2022
David C. Parkes
doaj   +1 more source

Teaching spatial data science

open access: yesGeoforum Perspektiv
Spatial data science is an emerging field building on geographic information science, geography, and data science. Here we first discuss the definition and history of the field, arguing that it indeed warrants a new label. Then, we present the design of
Ane Rahbek Vierø, Michael Szell
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Insightful Data Science

open access: yesHarvard Data Science Review, 2021
Hongyu Zhao
doaj   +1 more source

Responsible Data Science [PDF]

open access: yesBusiness & Information Systems Engineering, 2017
Aalst, Wil M. P. van der   +2 more
openaire   +1 more source

Artificial intelligence for imaging data analysis in materials science: microscopy and behind

open access: diamond, 2021
A. G. Okunev   +4 more
openalex   +1 more source

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