Results 81 to 90 of about 1,622,308 (337)
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Stark Broadening of several Ar I Spectral Lines in the Visible Part of the Spectrum
, 2011 In order to complete data on Stark broadening parameters for Ar I line in the visible spectrum, we determined Stark widths and shifts due to electron, proton, and ionized helium impacts, for nine lines (4191.0, 4259.4, 5912.1, 6043.2, 6045.0, 6752.9 ...
Bashkin +5 more
core +2 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
An Overview of Data Models of Object-Oriented DBMSs
Труды Института системного программирования РАН, 2018 Object-oriented DBMS theory is one of the most prospective areas of modern database theory, along with deductive and temporal DBMS. Nevertheless, a high variety of different approaches and absence of a uniform standard, both in theoretical OODBMS area ...
A. M. Eldarkhanov
doaj
Tableaux Modulo Theories Using Superdeduction
, 2014 We propose a method that allows us to develop tableaux modulo theories using the principles of superdeduction, among which the theory is used to enrich the deduction system with new deduction rules.
Berkani, Karim +3 more
core +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
On Quasi Cycles in Hypergraph Databases
IEEE Access, 2020 The notion of hypergraph cyclicity is important in numerous fields of application of hypergraph theory in computer science and relational database theory. The database scheme and query can be represented as a hypergraph.
Fayed F. M. Ghaleb +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source