Results 41 to 50 of about 773,776 (302)

Mapping OMIM Disease–Related Variations on Protein Domains Reveals an Association Among Variation Type, Pfam Models, and Disease Classes

Frontiers in Molecular Biosciences, 2021
Human genome resequencing projects provide an unprecedented amount of data about single-nucleotide variations occurring in protein-coding regions and often leading to observable changes in the covalent structure of gene products.
Castrense Savojardo, Giulia Babbi, Pier Luigi Martelli, Rita Casadio, Rita Casadio   +4 more
doaj   +1 more source

The PIR integrated protein databases and data retrieval system

Data Science Journal, 2006
The Protein Information Resource (PIR) provides many databases and tools to support genomic and proteomic research. PIR is a member of UniProt—Universal Protein Resource—the central repository of protein sequence and function, which maintains UniProt ...
H Huang, ZZ Hu, BE Suzek, CH Wu
doaj   +1 more source

Representing and analysing molecular and cellular function in the computer [PDF]

, 2000
Determining the biological function of a myriad of genes, and understanding how they interact to yield a living cell, is the major challenge of the post genome-sequencing era.
Eldridge, M, Gilbert, D, Helden, JV, Mancuso, R, Naim, A, Wernisch, L, Wodak, SJ   +6 more
core   +1 more source

NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps [PDF]

, 2013
Molecular biology knowledge can be systematically represented in a computer-readable form as a comprehensive map of molecular interactions. There exist a number of maps of molecular interactions containing detailed description of various cell mechanisms.
Barillot, Emmanuel, Calzone, Laurence, Cohen, David, Kuperstein, Inna, Pook, Stuart, Viara, Eric, Zinovyev, Andrei   +6 more
core   +5 more sources

PROTEIN IDENTIFICATION USING SEQUENCE DATABASES

Scientific Journal of Astana IT University, 2020
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of proteins in peptides and their sequencing using tandem mass spectrometry (MS/MS), has become widespread. The identification of peptides from the obtained MS/
Golenko Ye., A. Ismailova, Ye. Rais
doaj  

The Protein Identifier Cross-Referencing (PICR) service: reconciling protein identifiers across multiple source databases

BMC Bioinformatics, 2007
Background Each major protein database uses its own conventions when assigning protein identifiers. Resolving the various, potentially unstable, identifiers that refer to identical proteins is a major challenge.
Leinonen Rasko, Lin Quan, Reisinger Florian, Kerrien Samuel, Martens Lennart, Jones Philip, Côté Richard G, Apweiler Rolf, Hermjakob Henning   +8 more
doaj   +1 more source

Proteomic Analysis of Chloroplast-to-Chromoplast Transition in Tomato Reveals Metabolic Shifts Coupled with Disrupted Thylakoid Biogenesis Machinery and Elevated Energy-Production Components [PDF]

, 2012
A comparative proteomic approach was performed to identify differentially expressed proteins in plastids at three stages of tomato(Solanum lycopersicum) fruit ripening (mature-green, breaker, red). Stringent curation and processing of the data from three
Alba, Aldridge, Altschul, Andersson, Andon, Armbruster, Asano, Baginsky, Balmer, Bannai, Barry, Barsan, Benjamini, Benning, Bian, Birtić, Blanke, Booth, Botella-Pavía, Bouvier, Bouyssié, Bramley, Bräutigam, Cai, Camara, Chen, Chen, Cho, Deborde, Delmar, Delmar, Demartini, Dieterle, Egea, Egea, Emanuelsson, Emes, Fan, Faurobert, Ferro, Fischer, Harris, Heazlewood, Heazlewood, Hetherington, Huang, Issaq, Jebanathirajah, Jeong, Jimenez, Kahlau, Kato, Kato, Kleffmann, Krech, Lee, Li, Li, Liu, Liu, Liu, Ljubesić, Lopez-Juez, Lundquist, Lytovchenko, Maple, Maple, Marano, McAndrew, Millar, Moing, Neta-Sharir, Niewiadomski, Onishi, Osorio, Palma, Paoletti, Pech, Peng, Pierleoni, Pirrello, Plücken, Ren, Richly, Rocco, Rutschow, Schauer, Seigneurin-Berny, Shipman-Roston, Siddique, Simkin, Small, Smith, Spurr, Su, Sun, Suzuki, Thelen, Thimm, Thomson, Tiwari, Torgrip, van Wijk, Vitha, von Zychlinski, Waters, Yakir-Tamang, Zeng, Zhang, Zhu, Zybailov   +110 more
core   +1 more source

ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis [PDF]

, 2020
We present ProteoClade, a Python toolkit that performs taxa-specific peptide assignment, protein inference, and quantitation for multi-species proteomics experiments.
Held, Jason M, Mooradian, Arshag D, Naegle, Kristen M, van der Post, Sjoerd   +3 more
core   +2 more sources

Proteomics: taking over where genomics leaves off

Czech Journal of Genetics and Plant Breeding, 2010
The proteomic studies are simultaneously developed in several directions and significantly influence our notions on the capabilities of biological sciences.
Ritu MAHAJAN, Priyanka GUPTA
doaj   +1 more source

Comparative Assessment of Protein Kinase Inhibitors in Public Databases and in PKIDB

Molecules, 2020
Since the first approval of a protein kinase inhibitor (PKI) by the Food and Drug Administration (FDA) in 2001, 55 new PKIs have reached the market, and many inhibitors are currently being evaluated in clinical trials.
Colin Bournez, Fabrice Carles, Gautier Peyrat, Samia Aci-Sèche, Stéphane Bourg, Christophe Meyer, Pascal Bonnet   +6 more
doaj   +1 more source