Results 41 to 50 of about 296,992 (153)

HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions [PDF]

open access: yes, 2012
Background: The modeling of interactions among transcription factors (TFs) and their respective target genes (TGs) into transcriptional regulatory networks is important for the complete understanding of regulation of biological processes.
Luiz A. Bovolenta   +2 more
core   +4 more sources

The potential of text mining in data integration and network biology for plant research : a case study on Arabidopsis [PDF]

open access: yes, 2013
Despite the availability of various data repositories for plant research, a wealth of information currently remains hidden within the biomolecular literature. Text mining provides the necessary means to retrieve these data through automated processing of
De Bodt, Stefanie   +4 more
core   +2 more sources

TOPAZ: asymmetric suffix array neighbourhood search for massive protein databases

open access: yesBMC Bioinformatics, 2018
Background Protein homology search is an important, yet time-consuming, step in everything from protein annotation to metagenomics. Its application, however, has become increasingly challenging, due to the exponential growth of protein databases.
Alan Medlar, Liisa Holm
doaj   +1 more source

Prefix-Projection Global Constraint for Sequential Pattern Mining [PDF]

open access: yes, 2015
Sequential pattern mining under constraints is a challenging data mining task. Many efficient ad hoc methods have been developed for mining sequential patterns, but they are all suffering from a lack of genericity.
B Negrevergne   +7 more
core   +2 more sources

Protein Bioinformatics Databases and Resources [PDF]

open access: yes, 2010
In the past decades, a variety of publicly available data repositories and resources have been developed to support protein related information management, data-driven hypothesis generation and biological knowledge discovery. However, there is also an increasing confusion for the researchers who are trying to quickly find the appropriate resources to ...
Chuming, Chen   +2 more
openaire   +3 more sources

SPIDer: Saccharomyces protein-protein interaction database [PDF]

open access: yesBMC Bioinformatics, 2006
Abstract Background Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell, experimentally or computationally, is an important first step toward understanding cellular function and machinery of a proteome ...
Li Zhenbo   +8 more
openaire   +3 more sources

PrOnto Database : GO term functional dissimilarity inferred from biological data.

open access: yesFrontiers in Genetics, 2015
Moonlighting proteins are defined by their involvement in multiple, unrelated functions. The computational prediction of such proteins requires a formal method of assessing the similarity of cellular processes, for example, by identifying dissimilar Gene
Charles E Chapple   +6 more
doaj   +1 more source

Ontology-assisted database integration to support natural language processing and biomedical data-mining [PDF]

open access: yes, 2004
Successful biomedical data mining and information extraction require a complete picture of biological phenomena such as genes, biological processes, and diseases; as these exist on different levels of granularity.
Ceusters, Werner   +4 more
core   +1 more source

Computer-Aided Protein Directed Evolution: a Review of Web Servers, Databases and other Computational Tools for Protein Engineering

open access: yesComputational and Structural Biotechnology Journal, 2012
The combination of computational and directed evolution methods has proven a winning strategy for protein engineering. We refer to this approach as computer-aided protein directed evolution (CAPDE) and the review summarizes the recent developments in ...
Rajni Verma   +2 more
doaj   +3 more sources

Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases

open access: yesBMC Bioinformatics, 2007
Background In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from low-throughput experimental biomedical research literature, extracted ...
Ma'ayan Avi   +2 more
doaj   +1 more source

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