Results 91 to 100 of about 125,770 (300)

The db/db Mouse

open access: yes, 2014
Background: To characterize the sequential events that are taking place in retinal neurodegeneration in a murine model of spontaneous type 2 diabetes (db/db mouse). Methods: C57BLKsJ-db/db mice were used as spontaneous type 2 diabetic animal model, and C57BLKsJ-db/+ mice served as the control group.
Bogdanov, Patricia   +8 more
openaire   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Kv3 channel agonist ameliorates the phenotype of a mouse model of amyotrophic lateral sclerosis

open access: yesActa Neuropathologica Communications
Voltage-gated potassium channels, Kv3.1, Kv3.2, Kv3.3, and Kv3.4, facilitate rapid repolarization and shape action potentials, which are crucial to maintaining high-frequency firing.
Manuela Marabita   +28 more
doaj   +1 more source

Dried blood spots: An evaluation of utility in the field

open access: yesJournal of Infection and Public Health, 2018
Background: Use of dried blood spots (DBS) offers advantages over serum samples in studies conducted in resource-poor settings. The aim of this study was to compare the number of adequate spots collected across different demographic groups. Methods: Five
Xu Su   +9 more
doaj   +1 more source

Enhancement of Dielectric Breakdown Strength and Recoverable Energy Density in Three‐Dimensional Heterointerfaces on BaTiO3–PbZrO3–PbTiO3 Films via Room‐Temperature Nano‐Clustering

open access: yesAdvanced Functional Materials, EarlyView.
A room‐temperature aerosol deposition process yields multiphase nano‐clustered dielectric capacitors containing discrete BaTiO3, PbZrO3, and PbTiO3 crystals. This architecture creates three‐dimensional heterointerfaces that induce interfacial charge trapping and effectively inhibit breakdown propagation.
Hyunseok Song   +8 more
wiley   +1 more source

Human Trafficking and the Rome Statute of the International Criminal Court

open access: yesAge of Human Rights Journal, 2014
The case for extending the reach of the Rome Statute to the crime of human trafficking has not yet been made in detail. The brutality which occurs when human beings are trafficked by criminal gangs is of an equally egregious nature as the other crimes ...
Clare Frances Moran
doaj  

Deep brain stimulation is well tolerated and effective following ProSavin® gene therapy for Parkinson's disease

open access: yesNeurotherapeutics
Parkinson's disease (PD) is a neurodegenerative disorder initially treated with oral dopaminergic medications. When motor fluctuations and side effects develop on these treatments, Deep Brain stimulation (DBS) of the subthalamic nucleus (STN) is used ...
S. Senova   +11 more
doaj   +1 more source

Oxidized MoS2‐Based Multifunctional Memristive Hardware for Energy‐Efficient mmWave Signal Processing and In‐Memory Matrix Multiplication

open access: yesAdvanced Functional Materials, EarlyView.
Thermally oxidized MoS2‐based radio‐frequency switches enable a multifunctional platform that unifies broadband RF switching and in‐memory computation. The device achieves a cutoff frequency of 33.2 THz with high energy efficiency and supports hardware‐aware signal processing.
Juho Son   +5 more
wiley   +1 more source

Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization

open access: yesAdvanced Functional Materials, EarlyView.
We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat   +3 more
wiley   +1 more source

DB or not DB in translation? [PDF]

open access: yesMolecular Microbiology, 1999
Jean-Pierre Etchegaray, Masayori Inouye
openaire   +1 more source

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