Results 61 to 70 of about 861,339 (283)
Optimal PWM control of switched-capacitor DC/DC power converters via model transformation and enhancing control techniques [PDF]
, 2008 —This paper presents an efficient and effective method for an optimal pulse width modulated (PWM) control of switched-capacitor DC/DC power converters.
Ho, Charlotte Yuk-Fan +4 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Designing biologic selectivity for inflammatory bowel disease – role of vedolizumab
Drug Design, Development and Therapy, 2014 Niklas Krupka, Daniel C Baumgart Division of Gastroenterology and Hepatology, Department of Medicine, Charité Medical School, Humboldt-University of Berlin, Berlin, Germany Abstract: Crohn’s disease and ulcerative colitis are two chronic ...
Krupka N, Baumgart DC
doaj
Improving Adherence to Topical Medication in Patients with Glaucoma
Patient Preference and Adherence, 2021 Ian Tapply,1,2 David C Broadway1,3 1Department of Ophthalmology, Norfolk and Norwich University Hospital, Norwich, NR4 7UY, UK; 2Department of Ophthalmology, Addenbrooke’s Hospital, Cambridge, CB2 0QQ, UK; 3School of Pharmacy, University of East Anglia ...
Tapply I, Broadway DC
doaj
Plug and Play DC-DC Converters for Smart DC Nanogrids with Advanced Control Ancillary Services [PDF]
, 2018 This paper gives a general view of the control possibilities for dc-dc converters in dc nanogrids. A widely adopted control method is the droop control, which is able to achieve proportional load sharing among multiple sources and to stabilize the ...
Caldognetto, Tommaso +4 more
core +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Energy-aware MPC co-design for DC-DC converters [PDF]
, 2013 In this paper, we propose an integrated controller design methodology for the implementation of an energy-aware explicit model predictive control (MPC) algorithms, illustrat- ing the method on a DC-DC converter model.
Constantinides, George A. +3 more
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Review of dc-dc converters for multi-terminal HVDC transmission networks [PDF]
, 2016 This study presents a comprehensive review of high-power dc-dc converters for high-voltage direct current (HVDC) transmission systems, with emphasis on the most promising topologies from established and emerging dc-dc converters.
Ased, Grain Philip +4 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source