Results 171 to 180 of about 112,080 (220)

Optimising exercise intensity for gut health: Effect on microbiota composition, barrier integrity and inflammation in male Wistar rats

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise influences gut microbiota composition and intestinal permeability, but the optimal intensity for maintaining gut health remains unclear. This study investigates the effects of different exercise intensities on abundance of some gut microbiota, epithelial barrier integrity and inflammatory markers.
Nova Sylviana   +3 more
wiley   +1 more source

Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA

open access: yesExperimental Physiology, EarlyView.
Abstract Acute myocardial infarction (MI) accelerates cardiomyocyte apoptosis, which underpins ventricular remodelling and dysfunction. The hormone ghrelin mitigates this remodelling, but the mechanisms remain unclear. Specific microRNAs (miRs) are key modulators and reliable biomarkers of early‐stage apoptosis.
Rajesh Katare   +2 more
wiley   +1 more source

Cellular microenvironment of erythropoietin‐producing cells in hypoxic and injured mouse kidneys

open access: yesExperimental Physiology, EarlyView.
Abstract The main sources of circulating erythropoietin (Epo) in the adult are kidney Norn cells, a recently identified interstitial cell type capable of becoming renal Epo‐producing (REP) cells following a local decrease in tissue oxygenation. REP cells are restricted to small clusters in the corticomedullary border region, suggesting that their ...
Olga M. Lempke   +3 more
wiley   +1 more source

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra   +9 more
wiley   +1 more source

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