Results 61 to 70 of about 65,593 (219)
British Journal of Clinical Pharmacology, EarlyView.Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon +12 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Conversion of emestrin J (5) to emestrin (1) by three P450 enzymes from the cluster (eme) in Emericella quadrilineata. EmeO acts as a bifunctional enzyme for the construction of the 15‐membered lactone ring via an aryl‐aryl ether bond formation and simultaneous hydroxylation between phenolic and nonphenolic aromatic rings, while EmeE and EmeR install ...
Yu‐Chuan Chen +3 more
wiley +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The Antitrust of Reputation Mechanisms: Institutional Economics and Concerted Refusals to Deal [PDF]
, 2009 An agreement among competitors to refuse to deal with another party is traditionally per se illegal under the antitrust laws. But coordinated refusals to deal are often necessary to punish wrongdoers, and thus to deter undesirable behavior that state ...
Richman, Barak D.
core +1 more source
First experiences with the ATLAS Pixel Detector Control System at the Combined Test Beam 2004
, 2005 Detector control systems (DCS) include the read out, control and supervision of hardware devices as well as the monitoring of external systems like cooling system and the processing of control data.
Imhäuser +6 more
core +1 more source
Ketogenic diet for infantile epileptic spasms
Epilepsia Open, EarlyView.Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Evidence Based Library and Information Practice, 2019 A Review of: Lund, B., & Agbaji, D. (2018). Use of Dewey Decimal Classification by academic libraries in the United States. Cataloging and Classification Quarterly, 56(7), 653-661.
Jordan Patterson
doaj +1 more source
HILT : High-Level Thesaurus Project. Phase IV and Embedding Project Extension : Final Report [PDF]
, 2009 Ensuring that Higher Education (HE) and Further Education (FE) users of the JISC IE can find appropriate learning, research and information resources by subject search and browse in an environment where most national and institutional service providers -
Joseph, Anu +2 more
core
NIKEL: Electronics and data acquisition for kilopixels kinetic inductance camera
, 2012 A prototype of digital frequency multiplexing electronics allowing the real time monitoring of microwave kinetic inductance detector (MKIDs) arrays for mm-wave astronomy has been developed.
+14 more
core +4 more sources
iMetaOmics, EarlyView.This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang +7 more
wiley +1 more source