Results 61 to 70 of about 14,085 (196)

DDC-Chat: Achieving accurate distracted driver classification through instruction tuning of visual language model

Journal of Safety Science and Resilience
Driver behavior is a critical factor in road safety, highlighting the need for advanced methods in Distracted Driving Classification (DDC). In this study, we introduce DDC-Chat, a novel classification method based on a Visual large Language Model (VLM ...
Chupei Liao, Kuoyi Lin
doaj   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

Irradiated Liver Cancer Cell Vaccine Transfected With GM‐CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM‐CSF

Cell Proliferation, EarlyView.
Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song, Yujie Jiang, Yu Zhang, Danyi Ao, Chunjun Ye, Xiya Huang, Yingqiong Zhou, Hanle Yang, Ruolan Xia, Jiayuan Ai, Dandan Wan, Aiping Tong, Yuquan Wei, Xuemei He, Aqu Alu, Xiawei Wei   +15 more
wiley   +1 more source

Postprandial Glucagon Action in the Human Brain

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner, Stephanie Kullmann, Julia Hummel, Katsiaryna Prystupa, Elena Hosenfeld, Ralf Veit, Andreas L. Birkenfeld, Hans‐Ulrich Häring, Hubert Preissl, Andreas Fritsche, Andreas Peter, Martin Heni   +11 more
wiley   +1 more source

DDC Lesson Plan [PDF]

, 2023
This lesson is designed as a one-shot lecture to teach first-year library students how to classify under the Dewey Decimal Classification system. It is designed for students with little to no prior knowledge of the DDC, but can also serve as a useful refresher for those with prior knowledge.
openaire  

Global Citizenship in Clinical Training: A Qualitative Study Evaluating a Co‐Creation Approach to Community Oral Health Interventions

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Oral health plays a crucial role in overall well‐being, impacting general health, psychological health and quality of life. Vulnerable groups often face higher rates of oral health problems, exacerbating inequalities. This study evaluates the effectiveness of student‐delivered oral health interventions with these groups using a co‐
Mahdi Hussaini, Andrea Rodriguez, Clement Seeballuck   +2 more
wiley   +1 more source

Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury

Drug Design, Development and Therapy, 2016
Ya-Ru Wang,1,* Fei-Long Tian,2,* Ming-Xian Yan,1 Jin-Hua Fan,1 Li-Yun Wang,1 Rong-Guang Kuang,1 Yan-Qing Li3 1Department of Gastroenterology, Shandong Qianfoshan Hospital, Shandong University, 2Shandong University School of Medicine, 3Department of ...
Wang YR, Tian FL, Yan MX, Fan JH, Wang LY, Kuang RG, Li YQ   +6 more
doaj  

Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment

Nature Communications
DOPA Decarboxylase (DDC) has been proposed as a cerebrospinal fluid (CSF) biomarker with increased concentrations in Lewy body disorders (LBDs) and highest levels in patients receiving dopaminergic treatment.
Katharina Bolsewig, Eline A. J. Willemse, Pascual Sánchez-Juan, Alberto Rábano, Minerva Martínez, James D. Doecke, Giovanni Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors in ‘t Veld, Niklas Mattsson-Carlgren, Katerina Veverova, Christopher J. Fowler, Lynn Boonkamp, Marleen Koel-Simmelink, Zulaiga Hussainali, Daimy N. Ruiters, Lorenzo Gaetani, Andrea Toja, Juan Fortea, Yolande Pijnenburg, Afina W. Lemstra, Wiesje M. van der Flier, Jakub Hort, Markus Otto, Oskar Hansson, Lucilla Parnetti, Colin L. Masters, Alberto Lleó, Charlotte E. Teunissen, Marta Del Campo Milán   +31 more
doaj   +1 more source

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

Equine Veterinary Education, EarlyView.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald, J. P. Schramel, E. Haltmayer, N. M. Biermann   +3 more
wiley   +1 more source

Expression analysis of DDC, dACE2, and EPO genes in Moroccan COVID-19 patients: links to viral load and demographics

Journal of Infection in Developing Countries
Introduction: Interactions between host and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are incompletely understood. Studies have highlighted the roles of L-dopa decarboxylase (DDC), interferon-inducible truncated isoform of angiotensin-
Oumaima Laazaazia, Ahd Ouladlahsen, Safaa Aqillouch, Haya Altawalah, Rachid Noureddine, M’hammed Sarih, Pascal Pineau, Abderrahmane Maaroufi, Mustapha Lkhider, Sayeh Ezzikouri   +9 more
doaj   +1 more source