Results 41 to 50 of about 59,976,998 (309)
A comparative evaluation of genome assembly reconciliation tools
Genome Biology, 2017 Background The majority of eukaryotic genomes are unfinished due to the algorithmic challenges of assembling them. A variety of assembly and scaffolding tools are available, but it is not always obvious which tool or parameters to use for a specific ...
Hind Alhakami +2 more
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G3: Genes, Genomes, Genetics, 2020 In recent years, improved sequencing technology and computational tools have made de novo genome assembly more accessible. Many approaches, however, generate either an unphased or only partially resolved representation of a diploid genome, in which ...
llya Soifer +14 more
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Comparing de novo assemblers for 454 transcriptome data [PDF]
BMC Genomics, 2010 Roche 454 pyrosequencing has become a method of choice for generating transcriptome data from non-model organisms. Once the tens to hundreds of thousands of short (250-450 base) reads have been produced, it is important to correctly assemble these to estimate the sequence of all the transcripts. Most transcriptome assembly projects use only one program
Kumar, Sujai, Blaxter, Mark L
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dnAQET: a framework to compute a consolidated metric for benchmarking quality of de novo assemblies
BMC Genomics, 2019 Background Accurate de novo genome assembly has become reality with the advancements in sequencing technology. With the ever-increasing number of de novo genome assembly tools, assessing the quality of assemblies has become of great importance in genome ...
Gokhan Yavas, Huixiao Hong, Wenming Xiao
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NSIT: novel sequence identification tool. [PDF]
PLoS ONE, 2014 Novel sequences are DNA sequences present in an individual's genome but absent in the human reference assembly. They are predicted to be biologically important, both individual and population specific, and consistent with the known human migration paths.
Benjarath Pupacdi +3 more
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Extreme-Scale De Novo Genome Assembly [PDF]
, 2017 De novo whole genome assembly reconstructs genomic sequence from short, overlapping, and potentially erroneous DNA segments and is one of the most important computations in modern genomics. This work presents HipMER, a high-quality end-to-end de novo assembler designed for extreme scale analysis, via efficient parallelization of the Meraculous code ...
Evangelos Georganas +6 more
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Genome assembly using quantum and quantum-inspired annealing
Scientific Reports, 2021 Recent advances in DNA sequencing open prospects to make whole-genome analysis rapid and reliable, which is promising for various applications including personalized medicine.
A. S. Boev +7 more
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De novo transcriptome assembly
, 2019 de novo transcriptome assembly. These high quality reads were prepared for de novo transcriptome assembly using Trinity software with default parameters.
Francisco Correa (6947984)
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Kermit: linkage map guided long read assembly
Algorithms for Molecular Biology, 2019 Background With long reads getting even longer and cheaper, large scale sequencing projects can be accomplished without short reads at an affordable cost.
Riku Walve, Pasi Rastas, Leena Salmela
doaj +1 more source