Results 61 to 70 of about 59,976,998 (309)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
DRAP: de novo RNA-Seq Assembly Pipeline
, 2017 Année de la première version : 2017Mode de diffusion : service en ligneTrinity and Oases are two commonly used de novo transcriptome assemblers. The contig sets they produce are of good quality.
Guiguen, Yann +5 more
core +2 more sources
SATRAP: SOLiD Assembler TRAnslation Program. [PDF]
PLoS ONE, 2015 SOLiD DNA sequences are typically analyzed using a reference genome, while they are not recommended for de novo assembly of genomes or transcriptomes. This is mainly due to the difficulty in translating the SOLiD color-space data into normal base-space ...
Davide Campagna +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Chloroplast genome assembly approaches from NGS data
Journal of BioScience and Biotechnology, 2016 The advent of Next Generation Sequencing platforms led to increase of research in whole genome assembly algorithms and software. Illumina Genome Analyzer produces a large amount of sequencing data, with a shorted read length, higher coverage and ...
Zdravka Ivanova +3 more
doaj
Meta-IDBA: a de Novo assembler for metagenomic data [PDF]
Bioinformatics, 2011 Abstract Motivation: Next-generation sequencing techniques allow us to generate reads from a microbial environment in order to analyze the microbial community. However, assembling of a set of mixed reads from different species to form contigs is a bottleneck of metagenomic research. Although there are many assemblers for assembling reads
Peng, Y, Chin, FYL, Yiu, SM, Leung, HCM
openaire +3 more sources
O acordo de procedimento no projeto do novo código de processo civil: Análise perspectiva sobre questões de aplicação do novo instituto. [PDF]
, 2014 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Jurídicas. Direito.Esse trabalho tem como tema os acordos de procedimento, encontrado no artigo 189 do projeto de Lei 166/10 do Senado, e se propõe a primordialmente explicar ...
TREML, Ágata
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source