Results 71 to 80 of about 59,976,998 (309)

State of the art de novo assembly of human genomes from massively parallel sequencing data

Human Genomics, 2010
Recent studies in human genomes have demonstrated the use of de novo assemblies to identify genetic variations that are difficult for mapping-based approaches.
Li Yingrui, Hu Yujie, Bolund Lars, Wang Jun   +3 more
doaj   +1 more source

Telomere length de novo assembly of all 7 chromosomes and mitogenome sequencing of the model entomopathogenic fungus, Metarhizium brunneum, by means of a novel assembly pipeline

BMC Genomics, 2021
Background More accurate and complete reference genomes have improved understanding of gene function, biology, and evolutionary mechanisms. Hybrid genome assembly approaches leverage benefits of both long, relatively error-prone reads from third ...
Zack Saud, Alexandra M. Kortsinoglou, Vassili N. Kouvelis, Tariq M. Butt   +3 more
doaj   +1 more source

Gossamer — a resource-efficient de novo assembler [PDF]

Bioinformatics, 2012
Abstract Motivation: The de novo assembly of short read high-throughput sequencing data poses significant computational challenges. The volume of data is huge; the reads are tiny compared to the underlying sequence, and there are significant numbers of sequencing errors.
Thomas C. Conway, Jeremy Wazny, Andrew J. Bromage, Justin Zobel, Bryan Beresford-Smith   +4 more
openaire   +2 more sources

A intervenção de terceiros no projeto do novo Código de Processo Civil [PDF]

, 2012
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Jurídicas. Direito.O presente trabalho de conclusão de curso tem por objetivo desenvolver um breve estudo sobre o instituto da intervenção de terceiros no projeto do novo código ...
Werner, Daniel Henrique
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Bandage: interactive visualisation of de novo genome assemblies [PDF]

Bioinformatics, 2015
Abstract Summary While de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a B ioinformatics
Ryan R. Wick, Mark B. Schultz, Justin Zobel, Kathryn E. Holt   +3 more
openaire   +3 more sources

Clark's Nutcracker de novo assembly

, 2014
De novo assembly of the Clark's Nutcracker using CLC Genomics Workbench.
Fujita, Matthew K., Todd A. Castoe (184476), Schield, Drew R., Oyler-McCance, Sara J., Matthew K. Fujita (123478), Reyes-Velasco, Jacobo, Fike, Jennifer A., Ruggiero, Robert P., Drew R. Schield (626285), Castoe, Todd A., Jennifer A. Fike (184495), Tomback, Diana F., Jacobo Reyes-Velasco (626286), Audra L. Andrew (626287), Diana F. Tomback (161663), Sara J. Oyler-McCance (184490), Card, Daren C., Robert P. Ruggiero (615498), Andrew, Audra L., Daren C. Card (626284)   +19 more
core   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Plant assemble - Plant de novo genome assembly: assembly v2

, 2022
With the advancement of long-read sequencing technologies and associated bioinformatics tools, it has now become possible to de novo assemble complex plant genomes with unrivalled contiguity, completeness and correctness. As read lengths can surpass repeat lengths, the ability to assemble genomes de novo has dramatically improved, whereby complex plant
Scott Ferguson, Ashley Jones, Justin Borevitz   +2 more
openaire   +1 more source

DNA3890 de novo assembly

, 2017
List of contigs generated from the de novo assembly in CLC Genomics ...
John Sproul (3482006), David Maddison (3741301), Sproul, John, Maddison, David   +3 more
core   +1 more source