Results 101 to 110 of about 60,554,138 (296)

transcriptome-and-genome-assembly: transcriptome-and-genome-assembly Version 1.0.0

, 2015
<p><a href="url"></a></p> <p>Scripts to assemble de novo transcriptomes and genomes.</p> <a class="anchor" href="#pipelines-with-sample-data-sets"><span class="octicon octicon-link"></span></a ...
Jennifer Shelton
core   +1 more source

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts. [PDF]

, 2014
Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis of P.
Conway, David J, Conway, David J., Ollomo, Benjamin, Ollomo, B., Böhme, Ulrike, Berriman, Matthew, Thomas, A. W., Bohme, U., Rayner, Julian C., Otto, Thomas D, Rayner, Julian C, Otto, Thomas D., Spottiswoode, N., Newbold, C., Otto, T. D., Pain, A., Pain, Arnab, Thomas, Alan W., Rayner, J. C., Berriman, M., Sanders, M., Conway, D. J., Renaud, F., Sanders, Mandy, Quail, Michael, Renaud, François, Quail, M., Thomas, Alan W, Spottiswoode, Natasha, Newbold, Chris, Prugnolle, Franck   +30 more
core   +1 more source

Improved de novo genomic assembly for the domestic donkey

Science Advances, 2018
New donkey genome reference unveils chromosomal rearrangements potentially involved in equine speciation and hybrid sterility.
Renaud, Gabriel, Petersen, Bent, Seguin-Orlando, Andaine, Bertelsen, Mads Frost, Waller, Andrew, Newton, Richard, Paillot, Romain, Bryant, Neil, Vaudin, Mark, Librado, Pablo, Orlando, Ludovic   +10 more
openaire   +5 more sources

Annotated genome and transcriptome of the endangered Caribbean mountainous star coral (Orbicella faveolata) using PacBio long-read sequencing

BMC Genomics
Long-read sequencing is revolutionizing de-novo genome assemblies, with continued advancements making it more readily available for previously understudied, non-model organisms.
Benjamin D. Young, Olivia M. Williamson, Nicholas S. Kron, Natalia Andrade Rodriguez, Lys M. Isma, Nicholas J. MacKnight, Erinn M. Muller, Stephanie M. Rosales, Stephanie M. Sirotzke, Nikki Traylor-Knowles, Sara D. Williams, Michael S. Studivan   +11 more
doaj   +1 more source

Evaluating the fidelity of de novo short read metagenomic assembly using simulated data. [PDF]

PLoS ONE, 2011
A frequent step in metagenomic data analysis comprises the assembly of the sequenced reads. Many assembly tools have been published in the last years targeting data coming from next-generation sequencing (NGS) technologies but these assemblers have not ...
Miguel Pignatelli, Andrés Moya
doaj   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Draft Genome Sequences of Strains of Pasteurella multocida Isolated from the United Kingdom and the United States [PDF]

, 2013
Pasteurella multocida is a major pathogen of farm animals and has worldwide distribution. Here we report the draft genome sequences of four strains that were isolated from animals in the United Kingdom and the United States and represent pathogenic and ...
Mark P. Dagleish, Colin Bayne, Fontaine, Michael, Lainson, Frederick A, Bayne, Colin, Frederick A. Lainson, Michael Fontaine, J. Christopher Hodgson, Dagleish, Mark P, Hodgson, J Christopher   +9 more
core   +1 more source

CAPRG: sequence assembling pipeline for next generation sequencing of non-model organisms. [PDF]

PLoS ONE, 2012
Our goal is to introduce and describe the utility of a new pipeline "Contigs Assembly Pipeline using Reference Genome" (CAPRG), which has been developed to assemble "long sequence reads" for non-model organisms by leveraging a reference genome of a ...
Arun Rawat, Mohamed O Elasri, Kurt A Gust, Glover George, Don Pham, Leona D Scanlan, Chris Vulpe, Edward J Perkins   +7 more
doaj   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source