Results 171 to 180 of about 111,403 (262)

De novo genome assembly of the Edwardsiid anthozoan Edwardsia elegans. [PDF]

open access: yesG3 (Bethesda)
Rutlekowski AI   +4 more
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari   +10 more
wiley   +1 more source

Colora: a Snakemake workflow for complete chromosome-scale de novo genome assembly. [PDF]

open access: yesBioinformatics
Obinu L   +4 more
europepmc   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

open access: yesiMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang   +19 more
wiley   +1 more source

De novo genome assembly, annotation, and characterization of chemosensory genes in the camel ked (Hippobosca camelina). [PDF]

open access: yesBMC Genomics
Kebaso F   +8 more
europepmc   +1 more source

Warm‐wet transition restructures arid lake microbiomes and functional potential

open access: yesiMetaOmics, EarlyView.
This study summarizes how a long‐term warm‐dry to warm‐wet transition restructures microbiomes and functional potential in Lake Bosten, an arid lake in northwestern China. Warm‐wet hydroclimatic change increased water level and hydrological connectivity, while decreasing salinity and total nitrogen.
Zhen Shen   +8 more
wiley   +1 more source

De novo genome assembly of Yanbian cattle using PacBio HiFi and Hi-C combined with RNA-seq data. [PDF]

open access: yesSci Data
Fang W   +9 more
europepmc   +1 more source

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

open access: yesiMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei   +26 more
wiley   +1 more source

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