Results 51 to 60 of about 128,901 (311)

Structural and Material Properties of Chitin Nanofibers Produced Without Deacetylation Treatment

Nano Select
Deacetylation pretreatment is commonly applied to chitin nanofibers to introduce positive charges on their surface, increasing their fibrillation efficiency in water. However, without this treatment, chitin cannot be easily disintegrated into fibers with
Yuka Tomita, Tomohito Yagita, Yuto Kaku, Tsuguyuki Saito, Shuji Fujisawa   +4 more
doaj   +1 more source

Emerging roles of telomeric chromatin alterations in cancer [PDF]

, 2019
Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Biroccio, Annamaria, Cacchione, Stefano, Rizzo, Angela   +2 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Sirtuin as the target of anti-cancer therapy

Journal of Education, Health and Sport, 2020
Sirtuins is a group of nicotinamide dinucleotide (NAD +) - dependent, which have deacetylation and ADP-ribosylation activity. They work by detaching the acetyl group from the lysine residue of the histones, thanks to which they influence the control of ...
Marzena Baran, Paulina Anna Miziak, Katarzyna Bonio   +2 more
doaj   +1 more source

SYNTHESIS AND CHARACTERIZATION OF STARCH-CHITOSAN COMPOSITES [PDF]

, 2008
In this experiment, the composites based on chitosan-starch were synthesized at different weight ratios (3/7, 4/6, 5/5, 6/4, 7/3, 8/2, 9/1) by using 4 %v of glycerol as plasticizer.
., Kenfat, ., Wulandari, A., Tokok, Savitri, Emma, Suseno, Natalia   +4 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis

Frontiers in Pharmacology
IntroductionPeriodontitis is intricately related to systemic disorders and exerts a negative impact on quality of life. Recent studies have suggested a potential association between periodontitis and fatty acid oxidation (FAO), a key metabolic process ...
Yixuan Jiang, Xiu Yao, Zhizhong Jiang, Xiaomeng Liu, Boyuan Sun, Zhengyu Guan, Lin Zhou, Hongjiao Li   +7 more
doaj   +1 more source

Interindividual Differences in In Vitro Human Intestinal Microbial Conversion of 3-Acetyl-DON and 15-Acetyl-DON

Toxins, 2022
In order to evaluate the potential differences between 3-Ac-DON and 15-Ac-DON in the human intestinal microbial metabolism, human fecal samples were anaerobically cultured in vitro.
Fangfang Li, Jing Jin, Ivonne M. C. M. Rietjens, Fuguo Xing   +3 more
doaj   +1 more source

Development Of Ecologically Safe Technology Of Waste Mycelia Recycling [PDF]

, 2017
Chitosan is a cationic polymer derived by deacetylation of chitin obtained from crustaceans. Biodegradable and mucoadhesion properties of chitosan have recently led to increasing the interest.
Yegorova, O. (Oksana)
core   +2 more sources

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source