Results 71 to 80 of about 97,756 (253)

Nature‐Derived Chitosan Biopolymer: A Promising Candidate for Sustainable Electronics

Advanced Materials Technologies, EarlyView.
In the creation of environmentally friendly devices, nature‐derived chitosan biopolymer is a promising contender for sustainable electronic research. It can be utilized to create more ecologically friendly scalable gadgets and has a variety of uses in different active layers of electronics.
Joshua McDonald, Ali Nawaz, Amandeep Singh, Prashant Sonar   +3 more
wiley   +1 more source

Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C

Genetics and Molecular Biology, 2011
A potential strategy to combat obesity and its associated complications involves modifying gene expression in adipose cells to reduce lipid accumulation.
Lizcano Fernando, Romero Carolina, Diana Vargas   +2 more
doaj  

Chitin‐Chitosan Cryogels for the Reversible Sequestration and Recovery of Heavy Metals From Wastewater

Advanced Materials Technologies, EarlyView.
Chitin‐chitosan cryogels with degrees of N‐acetylation from 12.2% to 71.4% are fabricated by dissolution, coagulation and lyophilization for the sequestration of heavy metals from water. Colorimetry and differential pulse voltammetry showed controlled adsorption and desorption capacities for As5+, Co2+ and Cu2+, making this material attractive for ...
Marta García‐Castrillo, Maialen Uribarrena, Jorge Sáiz, Guillermo Copello, Erlantz Lizundia   +4 more
wiley   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Epigenetics in Oncohematology: Brief Review

Клиническая онкогематология, 2015
Objective. To discuss historical aspects of epigenetics as an independent branch of biology, as well as to describe post-translational modifications of DNA and histones (PTMs) as epigenetic events. Methods.
Anton Dmitrievich Shirin, G. I. Kaletin, O. Yu. Baranova   +2 more
doaj   +1 more source

ELL Inhibits E2F1 Transcriptional Activity by Enhancing E2F1 Deacetylation via Recruitment of Histone Deacetylase 1

, 2014
ELL (eleven-nineteen lysine-rich leukemia protein) was first identified as a translocation partner of MLL in acute myeloid leukemia; however, the exact mechanism of its action has remained elusive.
Liu, Xing, Zhang, Wei, Xiao, WH (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan, Peoples R China., Ouyang, Gang, Ji, Wei, Xiao, Wuhan   +5 more
core   +1 more source

Effect of Heterogeneous Deacetylation on the Properties of Northern Shrimp Chitin and Chitosan [PDF]

, 2020
The effect of alkaline treatment of shrimp chitin on the molecular weight, the degree of deacetylation and degree of crystallinity of the resulting chitosan is studied.
Kuchina, Y. (Yuliya), Dolgopiatova, Nataliia, Kuchina, Yuliya, Dyakina, Tatiana, Dyakina, T. (Tatiana), Volkova, Tatiana, Volkova, T. (Tatiana), Dolgopiatova, N. (Nataliia)   +7 more
core   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Potential of Chitosan From Local Crab (Portunus Pelagicus) to Enhance Storability of Musa Paradisiaca L.

Jurnal Bahan Alam Terbarukan, 2019
Potential waste of local crab carapace (Portunus pelagicus) as a source of chitosan as an active layer that can protect bananas has been studied. The process in this study consists of three stages.
Buanasari Buanasari, Warlan Sugiyo, Nur Fitriani, Suryaningsih Suryaningsih   +3 more
doaj   +1 more source