Results 91 to 100 of about 97,756 (253)
Coupling reaction of aryl halides with phenylboronic acid using chitosan-copper (II) complex extracted from Persian Gulf shrimp shell [PDF]
شیمی کاربردی روزIn this research, using a suitable method and in line with the development of green chemistry, chitosan particles were prepared through the process of deacetylation from Persian Gulf shrimp shell waste, and then a copper-based complex was successfully ...
Abdulhamid Dehghani +2 more
doaj +1 more source
Advanced Science, EarlyView.In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang +11 more
wiley +1 more source
SIRT1 promotes DNA repair activity and deacetylation of Ku70
, 2007 Human SIRT1 controls various physiological responses including cell fate, stress, and aging, through deacetylation of its specific substrate protein. In processing DNA damage signaling, SIRT1 attenuates a cellular apoptotic response by deacetylation of ...
Cho, Myung-Haeng +8 more
core +1 more source
Advanced Science, EarlyView.AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie +14 more
wiley +1 more source
Histone deacetylases: revealing the molecular base of dimorphism in pathogenic fungi
Microbial Cell, 2015 Fungi, as every living organism, interact with the external world and have to adapt to its fluctuations. For pathogenic fungi, such interaction involves adapting to the hostile environment of their host.
Alberto Elías-Villalobos +2 more
doaj +1 more source
Advanced Science, EarlyView.The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen +8 more
wiley +1 more source
Regulation of histone deacetylase 6 on heat stress and lipid metabolism in livestock and poultry
Siliao yanjiu, 2023 HDAC6 is a kind of deacetylase with special structure and function located in the cytoplasm, which regulates the abnormal protein degradation in the cell through protein ubiquitination and protein lysine acetylation, and affects the cell cycle ...
LI Qiu-yan +3 more
doaj
Advanced Science, EarlyView.Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source
An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management
Advanced Science, EarlyView.Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer +12 more
wiley +1 more source
Tubulin deacetylation and rHos2 protein blots
, 2013 Western blot analysis of rHos2 protein polyclonal anti-sera: Western blot analysis of rHos2 protein using polyclonal antisera raised from mice. Tubulin Deacetylation Blot data_F1000: Western blot analysis for tubulin Deacetyation by rHos2 protein.
G. Karthikeyan (456459) +4 more
core +1 more source